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Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCAUR324602:GIXU-2215-MONOMER.
CAUR324602:GIXU-2406-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1UniRule annotation
Ordered Locus Names:Caur_2182
AND
Name:tuf2UniRule annotation
Ordered Locus Names:Caur_2367
OrganismiChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Taxonomic identifieri324602 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesChloroflexineaeChloroflexaceaeChloroflexus
ProteomesiUP000002008 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401Elongation factor TuPRO_0000337353Add
BLAST

Proteomic databases

PRIDEiA9WFP3.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi324602.Caur_2367.

Structurei

3D structure databases

ProteinModelPortaliA9WFP3.
SMRiA9WFP3. Positions 2-401.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 209200tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni19 – 268G1By similarity
Regioni60 – 645G2By similarity
Regioni81 – 844G3By similarity
Regioni136 – 1394G4By similarity
Regioni174 – 1763G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
InParanoidiA9WFP3.
KOiK02358.
OMAiGMVICKP.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9WFP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKQKFERTK PHINVGTIGH VDHGKTTLTA AITKVLSLKG AAQFMAYDQI
60 70 80 90 100
DNAPEERARG ITIAIRHVEY QTDKRHYAHV DCPGHADYIK NMITGAAQMD
110 120 130 140 150
GAILVVSAPD GPMPQTREHI LLARQVQVPA IVVFLNKVDM MDDPELLELV
160 170 180 190 200
ELELRELLSK YGFPGDEIPI VRGSARNALE SPSKDINAPE YKCILELMNA
210 220 230 240 250
VDEYIPTPQR AVDQPFLMPI EDVFGIKGRG TVVTGRIERG KVKVGDTVEI
260 270 280 290 300
VGMTNDAPRR TVVTGVEMFQ KTLDEGIAGD NVGCLLRGIE RTDVERGQVL
310 320 330 340 350
CAPGSIKPHK KFEAQVYVLK KEEGGRHTPF FSGYRPQFYI RTTDVTGAIG
360 370 380 390 400
LPAGMEMVMP GDNVVMTIEL IVPVAIEEGL RFAIREGGRT VGAGVVTKIL

D
Length:401
Mass (Da):44,019
Last modified:February 5, 2008 - v1
Checksum:iC4B7152276442ED8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000909 Genomic DNA. Translation: ABY35393.1.
CP000909 Genomic DNA. Translation: ABY35576.1.
RefSeqiWP_012258047.1. NC_010175.1.
YP_001635782.1. NC_010175.1.
YP_001635965.1. NC_010175.1.

Genome annotation databases

EnsemblBacteriaiABY35393; ABY35393; Caur_2182.
ABY35576; ABY35576; Caur_2367.
GeneIDi5826640.
5826831.
KEGGicau:Caur_2182.
cau:Caur_2367.
PATRICi21415425. VBIChlAur28763_2469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000909 Genomic DNA. Translation: ABY35393.1.
CP000909 Genomic DNA. Translation: ABY35576.1.
RefSeqiWP_012258047.1. NC_010175.1.
YP_001635782.1. NC_010175.1.
YP_001635965.1. NC_010175.1.

3D structure databases

ProteinModelPortaliA9WFP3.
SMRiA9WFP3. Positions 2-401.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi324602.Caur_2367.

Proteomic databases

PRIDEiA9WFP3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABY35393; ABY35393; Caur_2182.
ABY35576; ABY35576; Caur_2367.
GeneIDi5826640.
5826831.
KEGGicau:Caur_2182.
cau:Caur_2367.
PATRICi21415425. VBIChlAur28763_2469.

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
InParanoidiA9WFP3.
KOiK02358.
OMAiGMVICKP.
OrthoDBiEOG6R5C6X.

Enzyme and pathway databases

BioCyciCAUR324602:GIXU-2215-MONOMER.
CAUR324602:GIXU-2406-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29366 / DSM 635 / J-10-fl.

Entry informationi

Entry nameiEFTU_CHLAA
AccessioniPrimary (citable) accession number: A9WFP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: July 22, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.