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A9WFP3

- EFTU_CHLAA

UniProt

A9WFP3 - EFTU_CHLAA

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Protein
Elongation factor Tu
Gene
tuf1, Caur_2182
tuf2, Caur_2367
Organism
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarity
Nucleotide bindingi81 – 855GTP By similarity
Nucleotide bindingi136 – 1394GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCAUR324602:GIXU-2215-MONOMER.
CAUR324602:GIXU-2406-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Tu
Short name:
EF-Tu
Gene namesi
Name:tuf1
Ordered Locus Names:Caur_2182
AND
Name:tuf2
Ordered Locus Names:Caur_2367
OrganismiChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Taxonomic identifieri324602 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesChloroflexineaeChloroflexaceaeChloroflexus
ProteomesiUP000002008: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401Elongation factor TuUniRule annotation
PRO_0000337353Add
BLAST

Proteomic databases

PRIDEiA9WFP3.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi324602.Caur_2367.

Structurei

3D structure databases

ProteinModelPortaliA9WFP3.
SMRiA9WFP3. Positions 2-401.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 209200tr-type G
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni19 – 268G1 By similarity
Regioni60 – 645G2 By similarity
Regioni81 – 844G3 By similarity
Regioni136 – 1394G4 By similarity
Regioni174 – 1763G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiGTEMCMP.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9WFP3-1 [UniParc]FASTAAdd to Basket

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MAKQKFERTK PHINVGTIGH VDHGKTTLTA AITKVLSLKG AAQFMAYDQI    50
DNAPEERARG ITIAIRHVEY QTDKRHYAHV DCPGHADYIK NMITGAAQMD 100
GAILVVSAPD GPMPQTREHI LLARQVQVPA IVVFLNKVDM MDDPELLELV 150
ELELRELLSK YGFPGDEIPI VRGSARNALE SPSKDINAPE YKCILELMNA 200
VDEYIPTPQR AVDQPFLMPI EDVFGIKGRG TVVTGRIERG KVKVGDTVEI 250
VGMTNDAPRR TVVTGVEMFQ KTLDEGIAGD NVGCLLRGIE RTDVERGQVL 300
CAPGSIKPHK KFEAQVYVLK KEEGGRHTPF FSGYRPQFYI RTTDVTGAIG 350
LPAGMEMVMP GDNVVMTIEL IVPVAIEEGL RFAIREGGRT VGAGVVTKIL 400
D 401
Length:401
Mass (Da):44,019
Last modified:February 5, 2008 - v1
Checksum:iC4B7152276442ED8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000909 Genomic DNA. Translation: ABY35393.1.
CP000909 Genomic DNA. Translation: ABY35576.1.
RefSeqiYP_001635782.1. NC_010175.1.
YP_001635965.1. NC_010175.1.

Genome annotation databases

EnsemblBacteriaiABY35393; ABY35393; Caur_2182.
ABY35576; ABY35576; Caur_2367.
GeneIDi5826640.
5826831.
KEGGicau:Caur_2182.
cau:Caur_2367.
PATRICi21415425. VBIChlAur28763_2469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000909 Genomic DNA. Translation: ABY35393.1 .
CP000909 Genomic DNA. Translation: ABY35576.1 .
RefSeqi YP_001635782.1. NC_010175.1.
YP_001635965.1. NC_010175.1.

3D structure databases

ProteinModelPortali A9WFP3.
SMRi A9WFP3. Positions 2-401.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 324602.Caur_2367.

Proteomic databases

PRIDEi A9WFP3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABY35393 ; ABY35393 ; Caur_2182 .
ABY35576 ; ABY35576 ; Caur_2367 .
GeneIDi 5826640.
5826831.
KEGGi cau:Caur_2182.
cau:Caur_2367.
PATRICi 21415425. VBIChlAur28763_2469.

Phylogenomic databases

eggNOGi COG0050.
HOGENOMi HOG000229290.
KOi K02358.
OMAi GTEMCMP.
OrthoDBi EOG6R5C6X.

Enzyme and pathway databases

BioCyci CAUR324602:GIXU-2215-MONOMER.
CAUR324602:GIXU-2406-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29366 / DSM 635 / J-10-fl.

Entry informationi

Entry nameiEFTU_CHLAA
AccessioniPrimary (citable) accession number: A9WFP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: September 3, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi