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A9WFP3

- EFTU_CHLAA

UniProt

A9WFP3 - EFTU_CHLAA

Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCAUR324602:GIXU-2215-MONOMER.
    CAUR324602:GIXU-2406-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tuf1UniRule annotation
    Ordered Locus Names:Caur_2182
    AND
    Name:tuf2UniRule annotation
    Ordered Locus Names:Caur_2367
    OrganismiChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
    Taxonomic identifieri324602 [NCBI]
    Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesChloroflexineaeChloroflexaceaeChloroflexus
    ProteomesiUP000002008: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 401401Elongation factor TuPRO_0000337353Add
    BLAST

    Proteomic databases

    PRIDEiA9WFP3.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi324602.Caur_2367.

    Structurei

    3D structure databases

    ProteinModelPortaliA9WFP3.
    SMRiA9WFP3. Positions 2-401.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 209200tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 268G1By similarity
    Regioni60 – 645G2By similarity
    Regioni81 – 844G3By similarity
    Regioni136 – 1394G4By similarity
    Regioni174 – 1763G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A9WFP3-1 [UniParc]FASTAAdd to Basket

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    MAKQKFERTK PHINVGTIGH VDHGKTTLTA AITKVLSLKG AAQFMAYDQI    50
    DNAPEERARG ITIAIRHVEY QTDKRHYAHV DCPGHADYIK NMITGAAQMD 100
    GAILVVSAPD GPMPQTREHI LLARQVQVPA IVVFLNKVDM MDDPELLELV 150
    ELELRELLSK YGFPGDEIPI VRGSARNALE SPSKDINAPE YKCILELMNA 200
    VDEYIPTPQR AVDQPFLMPI EDVFGIKGRG TVVTGRIERG KVKVGDTVEI 250
    VGMTNDAPRR TVVTGVEMFQ KTLDEGIAGD NVGCLLRGIE RTDVERGQVL 300
    CAPGSIKPHK KFEAQVYVLK KEEGGRHTPF FSGYRPQFYI RTTDVTGAIG 350
    LPAGMEMVMP GDNVVMTIEL IVPVAIEEGL RFAIREGGRT VGAGVVTKIL 400
    D 401
    Length:401
    Mass (Da):44,019
    Last modified:February 5, 2008 - v1
    Checksum:iC4B7152276442ED8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000909 Genomic DNA. Translation: ABY35393.1.
    CP000909 Genomic DNA. Translation: ABY35576.1.
    RefSeqiYP_001635782.1. NC_010175.1.
    YP_001635965.1. NC_010175.1.

    Genome annotation databases

    EnsemblBacteriaiABY35393; ABY35393; Caur_2182.
    ABY35576; ABY35576; Caur_2367.
    GeneIDi5826640.
    5826831.
    KEGGicau:Caur_2182.
    cau:Caur_2367.
    PATRICi21415425. VBIChlAur28763_2469.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000909 Genomic DNA. Translation: ABY35393.1 .
    CP000909 Genomic DNA. Translation: ABY35576.1 .
    RefSeqi YP_001635782.1. NC_010175.1.
    YP_001635965.1. NC_010175.1.

    3D structure databases

    ProteinModelPortali A9WFP3.
    SMRi A9WFP3. Positions 2-401.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 324602.Caur_2367.

    Proteomic databases

    PRIDEi A9WFP3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABY35393 ; ABY35393 ; Caur_2182 .
    ABY35576 ; ABY35576 ; Caur_2367 .
    GeneIDi 5826640.
    5826831.
    KEGGi cau:Caur_2182.
    cau:Caur_2367.
    PATRICi 21415425. VBIChlAur28763_2469.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci CAUR324602:GIXU-2215-MONOMER.
    CAUR324602:GIXU-2406-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29366 / DSM 635 / J-10-fl.

    Entry informationi

    Entry nameiEFTU_CHLAA
    AccessioniPrimary (citable) accession number: A9WFP3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3