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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene

gatA

Organism
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei80Charge relay systemUniRule annotation1
Active sitei155Charge relay systemUniRule annotation1
Active sitei179Acyl-ester intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCAUR324602:G1GAO-1737-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation (EC:6.3.5.7UniRule annotation)
Short name:
Glu-ADT subunit AUniRule annotation
Gene namesi
Name:gatAUniRule annotation
Ordered Locus Names:Caur_1712
OrganismiChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Taxonomic identifieri324602 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesChloroflexineaeChloroflexaceaeChloroflexus
Proteomesi
  • UP000002008 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002030261 – 487Glutamyl-tRNA(Gln) amidotransferase subunit AAdd BLAST487

Proteomic databases

PRIDEiA9WCD8

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Protein-protein interaction databases

STRINGi324602.Caur_1712

Structurei

3D structure databases

ProteinModelPortaliA9WCD8
SMRiA9WCD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family. GatA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3P Bacteria
COG0154 LUCA
HOGENOMiHOG000116697
InParanoidiA9WCD8
KOiK02433
OMAiPITQNVE
OrthoDBiPOG091H00O9

Family and domain databases

Gene3Di3.90.1300.10, 1 hit
HAMAPiMF_00120 GatA, 1 hit
InterProiView protein in InterPro
IPR000120 Amidase
IPR020556 Amidase_CS
IPR023631 Amidase_dom
IPR036928 AS_sf
IPR004412 GatA
PANTHERiPTHR11895 PTHR11895, 1 hit
PfamiView protein in Pfam
PF01425 Amidase, 1 hit
SUPFAMiSSF75304 SSF75304, 1 hit
TIGRFAMsiTIGR00132 gatA, 1 hit
PROSITEiView protein in PROSITE
PS00571 AMIDASES, 1 hit

Sequencei

Sequence statusi: Complete.

A9WCD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTELHHLTVT AAQAALAAGD ITAVELTEAC LARINATEPT IRAFLHLTPD
60 70 80 90 100
AALAAARAAD ERRQQGRSLG PLDGIPIAIK DVICTDGVPT TAGSRILAGF
110 120 130 140 150
RPPYNATVIE RLVAAGAVLV GKLNCDEFAM GSSTENSAYQ ITTNPWDPTR
160 170 180 190 200
VPGGSSGGSA AAVAAGQVPA TLGTDTGGSI RQPAALCGIS GLKPTYGRVS
210 220 230 240 250
RYGLIAYGSS LDQIGPMAWT VADLAVLLNV IAGHDPRDGT SAPIDTPDYT
260 270 280 290 300
TALTGDIRGL RIGIPREYFV EGMEPGVESA TRTAIEVLRD LGAILVDVSL
310 320 330 340 350
PHTRYALPTY YIIAPAEASA NLARFDGVRY GFRAEGETMW EQIEQTRGQG
360 370 380 390 400
FGPEVRRRIM LGTYALSAGY YDAYYRRAQQ VRTLIKRDFE QVFTQVDLLA
410 420 430 440 450
APTSPTVAFP IGQKINDPLA MYLSDVCTLP INLAGVPALV VPCGFSEGLP
460 470 480
VGLQLIGRPF DEATLLRVGD AYQRLTEWHT QRPRLVV
Length:487
Mass (Da):51,878
Last modified:February 5, 2008 - v1
Checksum:iDBE869A4708E5A2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000909 Genomic DNA Translation: ABY34929.1
RefSeqiWP_012257583.1, NC_010175.1
YP_001635318.1, NC_010175.1

Genome annotation databases

EnsemblBacteriaiABY34929; ABY34929; Caur_1712
GeneIDi5826161
KEGGicau:Caur_1712
PATRICifig|324602.8.peg.1952

Similar proteinsi

Entry informationi

Entry nameiGATA_CHLAA
AccessioniPrimary (citable) accession number: A9WCD8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: February 5, 2008
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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