A9WBS2 (A9WBS2_CHLAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401
Ordered Locus Names:	Caur_1661

Organism

Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) EMBL ABY34879.1

Taxonomic identifier

324602 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length	181 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ABY34879.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	12	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A9WBS2 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 43FEAA780842F7DE	FASTA	181	20,642
	10 20 30 40 50 60 MPLETATLAG GCFWCLEAVY DQVSGVKDVV SGYTGGYVPN PTYRRVCDGN TGHAEAVQIQ 70 80 90 100 110 120 FDPEQISYRE LLEIFFSIHD PTTLNRQGAD VGTQYRSAIF YHSEEQRQVA EQLVRELTEQ 130 140 150 160 170 180 QVFRDPIVTQ IVPATTFYPA EEYHQEYFAR NPYQPYCQFV VAPKVAKFQK LFAHRVAGEK S

References

[1]

"Complete sequence of Chloroflexus aurantiacus J-10-fl." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Pierson B.K., Blankenship R.E., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29366 / DSM 635 / J-10-fl.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000909 Genomic DNA. Translation: ABY34879.1.
RefSeq	YP_001635268.1. NC_010175.1.
3D structure databases
ProteinModelPortal	A9WBS2.
ModBase	Search...
Protein-protein interaction databases
STRING	A9WBS2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5826110.
GenomeReviews	Gene locus Caur_1661 in contig CP000909_GR.
KEGG	cau:Caur_1661.
PATRIC	21414271. VBIChlAur28763_1900.
Phylogenomic databases
HOGENOM	HBG748152.
OMA	EDKIVTE.
PhylomeDB	A9WBS2.
ProtClustDB	CLSK2476952.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9WBS2_CHLAA

Accession

Primary (citable) accession number: A9WBS2

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)