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A9WA97 (SYN_CHLAA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Asparagine--tRNA ligase
EC=6.1.1.22
Alternative name(s):
Asparaginyl-tRNA synthetase
Short name=AsnRS
Gene names
Name:asnS
Ordered Locus Names:Caur_1428
OrganismChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Taxonomic identifier324602 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn). HAMAP MF_00534

Subunit structure

Homodimer By similarity. HAMAP MF_00534

Subcellular location

Cytoplasm By similarity HAMAP MF_00534.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processasparaginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

asparagine-tRNA ligase activity

Inferred from electronic annotation. Source: EC

nucleic acid binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Asparagine--tRNA ligase HAMAP MF_00534
PRO_1000081845

Sequences

Sequence LengthMass (Da)Tools
A9WA97 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 9FA56F03C01D8690

FASTA44050,042
        10         20         30         40         50         60 
MSLLPTATVA TIARYVGQRV TLAGWVYHKT EKGKLIFILL RDGSGTIQCV TFKKNVSEET 

        70         80         90        100        110        120 
FATAQSLTQE SSCRITGSVR ADERAPGGYE LDVESIELIG PSHEYPITPK EHGVEFLMAH 

       130        140        150        160        170        180 
RHLWVRSAKQ HAILRIRAEV IAAAQEWLNE QGFVRFDTPI LTATAAEGTT NLFATDYFDL 

       190        200        210        220        230        240 
GKAYLAQTGQ LYVEAGMMAF GKVYCFGPTF RAEKSKTRRH LTEFWMIEPE VAFADHEDNM 

       250        260        270        280        290        300 
RLQEEFVSAI VARVLERRRD DLQTLERDTT LLEQVRPPFP RITYDEAIEL IAAHQGEVEG 

       310        320        330        340        350        360 
ADPLPWGEDF GAPHETLIAS KFDRPVFVER FPSAVKAFYM QPDPERPEVA LCADLLAPEG 

       370        380        390        400        410        420 
YGEIIGGSQR IHDPILLEQR IREHGLRIED YEWYLDLRRY GTVPHSGFGM GIERVVAWIT 

       430        440 
GTRHIRETIP FPRQLYRIYP

« Hide

References

[1]"Complete sequence of Chloroflexus aurantiacus J-10-fl."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Pierson B.K., Blankenship R.E., Richardson P.
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29366 / DSM 635 / J-10-fl.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000909 Genomic DNA. Translation: ABY34656.1.
RefSeqYP_001635045.1. NC_010175.1.

3D structure databases

ProteinModelPortalA9WA97.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9WA97.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5828534.
GenomeReviewsGene locus Caur_1428 in contig CP000909_GR.
KEGGcau:Caur_1428.
PATRIC21413713. VBIChlAur28763_1623.

Phylogenomic databases

HOGENOMHBG745843.
OMADHLPQET.
PhylomeDBA9WA97.
ProtClustDBPRK03932.

Family and domain databases

HAMAPMF_00534. Asn_tRNA_synth.
[Tree]
InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004522. Asn-tRNA-synth_IIb.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR012340. NA-bd_OB-fold.
IPR016027. NA-bd_OB-fold-like.
IPR004365. NA-bd_OB_tRNA-helicase.
[Graphical view]
Gene3DG3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KOK01893.
PANTHERPTHR22594. aa-tRNA-synt_II. 1 hit.
PTHR22594:SF6. PTHR22594:SF6. 1 hit.
PfamPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR01042. TRNASYNTHASP.
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMsTIGR00457. AsnS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYN_CHLAA
AccessionPrimary (citable) accession number: A9WA97
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

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