A9W6X7 (URED3_METEP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreD 3

Gene names

Name:	ureD3
Ordered Locus Names:	Mext_3020

Organism

Methylobacterium extorquens (strain PA1) [Complete proteome] [HAMAP]

Taxonomic identifier

419610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01384
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01384.
Sequence similarities	Belongs to the UreD family.
Sequence caution	The sequence ABY31409.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 298	298	Urease accessory protein UreD 3 HAMAP MF_01384		PRO_0000346574

Sequences

	Sequence		Length	Mass (Da)
	A9W6X7 [UniParc]. Last modified September 2, 2008. Version 2. Checksum: A6172E3123FA2987	FASTA	298	31,601
	10 20 30 40 50 60 MADEAGTRSA GGRPIPAAEP LRPALSRQRS QGAVHLRVAP AGTAADAPTR IVDLAESGPL 70 80 90 100 110 120 RLRCPRQGAE RMLEGVLVNT GGGIACGDVF TVSVTVEPGG ACVLTTTAAE KIYRSDGPCA 130 140 150 160 170 180 EIVNRASVGA GGRLDWLPQE TILFDRARLV RRFEADLAPD ASLLVAEIAV LGRAARGESL 190 200 210 220 230 240 EQALFEDRWR IRRDGRLVYA DSLRLDGAVT ALMNRRAIGG GARALATILD LSLRAEGRLD 250 260 270 280 290 EARALLDALP AQVEAGASAW NGHLAVRMLA PTVAPLRDAA ARFLAAWRGQ PMPRVWQT

References

[1]

"Complete sequence of Methylobacterium extorquens PA1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Marx C., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PA1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000908 Genomic DNA. Translation: ABY31409.1. Different initiation.
RefSeq	YP_001640480.1. NC_010172.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A9W6X7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5835424.
GenomeReviews	Gene locus Mext_3020 in contig CP000908_GR.
KEGG	mex:Mext_3020.
PATRIC	22536616. VBIMetExt98426_3057.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG711156.
OMA	QETILFD.
ProtClustDB	CLSK980186.
Enzyme and pathway databases
BioCyc	MEXT419610:MEXT_3020-MONOMER.
Family and domain databases
HAMAP	MF_01384. UreD. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
KO	K03190.
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

URED3_METEP

Accession

Primary (citable) accession number: A9W6X7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	January 25, 2012
This is version 24 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program