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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Methylobacterium extorquens (strain PA1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMEXT419610:GI32-3010-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:Mext_2960
OrganismiMethylobacterium extorquens (strain PA1)
Taxonomic identifieri419610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000008546 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 639639Chaperone protein DnaKPRO_1000119727Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei198 – 1981Phosphothreonine; by autocatalysisUniRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiA9W6R7.

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi419610.Mext_2960.

Structurei

3D structure databases

ProteinModelPortaliA9W6R7.
SMRiA9W6R7. Positions 1-595.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.
OrthoDBiPOG091H01UE.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9W6R7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKVIGIDLG TTNSCVAVME GTQPRVIENA EGARTTPSIV AFTDDGERLV
60 70 80 90 100
GQPAKRQAVT NPERTFFAIK RLIGRTYDDP LTQKDKGLVP YKIARGDNGD
110 120 130 140 150
AWVEADGKKY SPSQISAFTL QKMKETAESH LGQPVTQAVI TVPAYFNDAQ
160 170 180 190 200
RQATKDAGKI AGLEVLRIIN EPTAAALAYG LDKKKAGTIA VYDLGGGTFD
210 220 230 240 250
VSILEIGDGV FEVKSTNGDT FLGGEDFDNR VVEYLTAEFK KEQGIDLTKD
260 270 280 290 300
KLALQRLKEA AEKAKIELSS ATQTEINLPY ITADASGPKH LALKLSRAKF
310 320 330 340 350
ESLVDDLVQR TIEPCRKALK DAGVSASEID EVVLVGGQTR MPKVQEVVKA
360 370 380 390 400
FFGKEPHKGV NPDEVVAIGA AVQAGVLQGD VKDVLLLDVT PLSLGIETLG
410 420 430 440 450
GVFTRLIDRN TTIPTKKSQV FSTAEDNQNA VTIRVFQGER EMAADNKLLG
460 470 480 490 500
QFDLVGIPPA PRGMPQIEVT FDIDANGIVN VTAKDKATNK EHQIRIQASG
510 520 530 540 550
GLSDADIEKM VKDAEANAEA DKKRRELVEV KNQGESLIHA TEKSVSEYGD
560 570 580 590 600
KVSAADKGAI ESAITALRSA LEGEDAEGIK AKTNDLMQAS MKLGEAMYAA
610 620 630
SQTEGAPGAD GAASTDEKKD DVIDADFQEV DENERKKRA
Length:639
Mass (Da):68,620
Last modified:February 5, 2008 - v1
Checksum:iB86F9C404FA2ED31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000908 Genomic DNA. Translation: ABY31349.1.
RefSeqiWP_003603957.1. NC_010172.1.

Genome annotation databases

EnsemblBacteriaiABY31349; ABY31349; Mext_2960.
KEGGimex:Mext_2960.
PATRICi22536494. VBIMetExt98426_2996.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000908 Genomic DNA. Translation: ABY31349.1.
RefSeqiWP_003603957.1. NC_010172.1.

3D structure databases

ProteinModelPortaliA9W6R7.
SMRiA9W6R7. Positions 1-595.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi419610.Mext_2960.

Proteomic databases

PRIDEiA9W6R7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABY31349; ABY31349; Mext_2960.
KEGGimex:Mext_2960.
PATRICi22536494. VBIMetExt98426_2996.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.
OrthoDBiPOG091H01UE.

Enzyme and pathway databases

BioCyciMEXT419610:GI32-3010-MONOMER.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_METEP
AccessioniPrimary (citable) accession number: A9W6R7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.