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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Methylobacterium extorquens (strain PA1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:Mext_2474
OrganismiMethylobacterium extorquens (strain PA1)
Taxonomic identifieri419610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000008546 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000929551 – 210Peptidyl-tRNA hydrolaseAdd BLAST210

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi419610.Mext_2474

Structurei

3D structure databases

ProteinModelPortaliA9W5L3
SMRiA9W5L3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004796
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

A9W5L3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLIVGLGNP GARYARNRHN IGFMAVDEIA RVHRAAPFRR RFQGEAAEVM
60 70 80 90 100
LGSERAILLK PQTFMNESGR SVGEAQRFFK IPLADVIVLH DELDLAPAKL
110 120 130 140 150
RVKLGGGNAG HNGLRSITAL CGNEYRRVRL GIGHPGDKAL VHAYVLNDFA
160 170 180 190 200
KSEEPWVEDL CRATADHAPL LAAGEDASFQ NKVHLAMAGR GWETVKTPAE
210
AGKAKARDAN
Length:210
Mass (Da):22,894
Last modified:February 5, 2008 - v1
Checksum:iD1CC1521A590C3E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000908 Genomic DNA Translation: ABY30869.1
RefSeqiWP_003598133.1, NC_010172.1

Genome annotation databases

EnsemblBacteriaiABY30869; ABY30869; Mext_2474
KEGGimex:Mext_2474

Similar proteinsi

Entry informationi

Entry nameiPTH_METEP
AccessioniPrimary (citable) accession number: A9W5L3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: May 23, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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