Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A9W5B4

- GLSA_METEP

UniProt

A9W5B4 - GLSA_METEP

Protein

Glutaminase

Gene

glsA

Organism
Methylobacterium extorquens (strain PA1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei64 – 641SubstrateUniRule annotation
    Binding sitei114 – 1141SubstrateUniRule annotation
    Binding sitei160 – 1601SubstrateUniRule annotation
    Binding sitei167 – 1671SubstrateUniRule annotation
    Binding sitei191 – 1911SubstrateUniRule annotation
    Binding sitei243 – 2431SubstrateUniRule annotation
    Binding sitei261 – 2611Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciMEXT419610:GI32-2418-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:Mext_2375
    OrganismiMethylobacterium extorquens (strain PA1)
    Taxonomic identifieri419610 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
    ProteomesiUP000008546: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 309309GlutaminasePRO_1000119532Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi419610.Mext_2375.

    Structurei

    3D structure databases

    ProteinModelPortaliA9W5B4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OMAiQRARRIN.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A9W5B4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPDLDSIVKD IAAEMRARPD RGAVASYIPE LARVDAQGFG LVVIDGEGRV    50
    AAGGDADTPF SIQSISKVFT LTLALGMVGD RLWRRVGREP SGSPFNSIVQ 100
    LEREHGIPRN PFINAGAIAV TDLILSGHQP REALGEILRF MQFVAQDDSI 150
    TIDERVAASE KRTGFRNAAL ANYMRSFDVI ENPVDYTLGV YFHHCAIAMT 200
    CRQLATAGLF LAYSGHHPLA GHSVISAERA RRINAIMLTC GHYDGSGDFA 250
    YRVGLPGKSG VGGGILAVAP GKASICVWSP GLDAAGNSHL GRIALEMLVK 300
    RTGWSIFGV 309
    Length:309
    Mass (Da):33,045
    Last modified:February 5, 2008 - v1
    Checksum:iAF8CCC16BBC3A551
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000908 Genomic DNA. Translation: ABY30770.1.
    RefSeqiYP_001639841.1. NC_010172.1.

    Genome annotation databases

    EnsemblBacteriaiABY30770; ABY30770; Mext_2375.
    GeneIDi5831819.
    KEGGimex:Mext_2375.
    PATRICi22535270. VBIMetExt98426_2391.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000908 Genomic DNA. Translation: ABY30770.1 .
    RefSeqi YP_001639841.1. NC_010172.1.

    3D structure databases

    ProteinModelPortali A9W5B4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 419610.Mext_2375.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABY30770 ; ABY30770 ; Mext_2375 .
    GeneIDi 5831819.
    KEGGi mex:Mext_2375.
    PATRICi 22535270. VBIMetExt98426_2391.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OMAi QRARRIN.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci MEXT419610:GI32-2418-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PA1.

    Entry informationi

    Entry nameiGLSA_METEP
    AccessioniPrimary (citable) accession number: A9W5B4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3