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A9W5A7

- PGK_METEP

UniProt

A9W5A7 - PGK_METEP

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Protein

Phosphoglycerate kinase

Gene
pgk, Mext_2368
Organism
Methylobacterium extorquens (strain PA1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381Substrate By similarity
Binding sitei120 – 1201Substrate By similarity
Binding sitei153 – 1531Substrate By similarity
Binding sitei203 – 2031ATP By similarity
Binding sitei325 – 3251ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi355 – 3584ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMEXT419610:GI32-2411-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Mext_2368
OrganismiMethylobacterium extorquens (strain PA1)
Taxonomic identifieri419610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
ProteomesiUP000008546: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Phosphoglycerate kinaseUniRule annotationPRO_1000203340Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi419610.Mext_2368.

Structurei

3D structure databases

ProteinModelPortaliA9W5A7.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni23 – 253Substrate binding By similarity
Regioni61 – 644Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiVAKEFAP.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9W5A7-1 [UniParc]FASTAAdd to Basket

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MTDFRTLDDA GPLQGKRVLL RVDLNVPMEG GRVTDATRIE RVVPTIREIA    50
DAGGRVILLA HFGRPKGKPD PKDSLKPILS TLSEKLGRPV AFGEDCVGEA 100
AASAIAALKD GDVILLENTR YHAGEEKNDP DFAKALAANG DIYVNEAFSA 150
AHRAHASTEA LARLLPAYAG RLMQAELDAL TKGLEAPARP VIAIVGGAKV 200
STKIDLLENL VAKVDMLVIG GGMANTFLHA QGKDVGKSLC EKDLAETAKR 250
ILAAAKEKNC TIILPVDALV AREFKANAEN ETVPVDAVPS DAMILDVGAS 300
SIATIDGAIE EARTLVWNGP LGAFELTPFD TGTVAVAQHA ARRTKAGQLV 350
SVAGGGDTVA ALNHAGVGED FSYVSTAGGA FLEWLEGKEL PGVEALRAQG 400
Length:400
Mass (Da):41,819
Last modified:February 5, 2008 - v1
Checksum:i003B4822A9088A1C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000908 Genomic DNA. Translation: ABY30763.1.
RefSeqiYP_001639834.1. NC_010172.1.

Genome annotation databases

EnsemblBacteriaiABY30763; ABY30763; Mext_2368.
GeneIDi5833578.
KEGGimex:Mext_2368.
PATRICi22535256. VBIMetExt98426_2384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000908 Genomic DNA. Translation: ABY30763.1 .
RefSeqi YP_001639834.1. NC_010172.1.

3D structure databases

ProteinModelPortali A9W5A7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 419610.Mext_2368.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABY30763 ; ABY30763 ; Mext_2368 .
GeneIDi 5833578.
KEGGi mex:Mext_2368.
PATRICi 22535256. VBIMetExt98426_2384.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi VAKEFAP.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci MEXT419610:GI32-2411-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PA1.

Entry informationi

Entry nameiPGK_METEP
AccessioniPrimary (citable) accession number: A9W5A7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: February 5, 2008
Last modified: June 11, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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