A9W482 (A9W482_METEP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase EMBL ABY30388.1
EC=2.3.1.37 EMBL ABY30388.1

Gene names

Ordered Locus Names:

Mext_1989

Organism

Methylobacterium extorquens (strain PA1) [Complete proteome] [HAMAP]

Taxonomic identifier

419610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	462 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Acyltransferase EMBL ABY30388.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9W482 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: A1F9AA6F95E363A4	FASTA	462	49,657
	10 20 30 40 50 60 MPVNLMPVNA ADSASLTDES IVGGDGGVDD SGASNGRAKF ERPPVRPAGP RTDYDGHFRA 70 80 90 100 110 120 ALDRLHSERR YRVFADIERI SGRFPQATWR RPEGGNREIT VWCSNDYLGM GQHPEVVAAL 130 140 150 160 170 180 TDTAARCGVG AGGTRNIAGN NSPLVDLERE LADLHGKEAG LVFTSGYVSN QAGISTIAKL 190 200 210 220 230 240 LPNCLILSDA FNHNSMIEGV RHSGCEKRVF RHNDLEHLEQ LLAEAGDRPK LIAFESVYSM 250 260 270 280 290 300 DGDVAPIAAI CDLADAYGAM TYLDEVHAVG LYGERGAGIA ERDRVMHRVD VIEGTLAKGF 310 320 330 340 350 360 GCVGGYITGT ATLCDAVRSH AAGFIFTTAL PPAVAAAARA SVRYLKRSKT EREAHQRQAA 370 380 390 400 410 420 RTKAALEAAG LPVLHTETHI VPLMVGDAEL CKAAADHLLE HHDIYIQPIN YPTVPRGTER 430 440 450 460 LRITPSPFHD DERIGALTAA LVETWDTLDL PRAGTVFAAA AE

References

[1]

"Complete sequence of Methylobacterium extorquens PA1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Marx C., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PA1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000908 Genomic DNA. Translation: ABY30388.1.
RefSeq	YP_001639459.1. NC_010172.1.
3D structure databases
ProteinModelPortal	A9W482.
SMR	A9W482. Positions 53-445.
ModBase	Search...
Protein-protein interaction databases
STRING	A9W482.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5833876.
GenomeReviews	Gene locus Mext_1989 in contig CP000908_GR.
KEGG	mex:Mext_1989.
PATRIC	22534477. VBIMetExt98426_1997.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG649839.
OMA	HATWHSP.
ProtClustDB	PRK09064.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9W482_METEP

Accession

Primary (citable) accession number: A9W482

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)