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A9W3P4

- A9W3P4_METEP

UniProt

A9W3P4 - A9W3P4_METEP

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylobacterium extorquens (strain PA1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei142 – 1421UniRule annotation
    Active sitei581 – 5811UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciMEXT419610:GI32-1841-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    Ordered Locus Names:Mext_1801Imported
    OrganismiMethylobacterium extorquens (strain PA1)Imported
    Taxonomic identifieri419610 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
    ProteomesiUP000008546: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi419610.Mext_1801.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2352.
    HOGENOMiHOG000238647.
    KOiK01595.
    OMAiYNAPIIQ.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A9W3P4-1 [UniParc]FASTAAdd to Basket

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    MTKTLHARPS AATDTTFAPP VITGTATEDA LEILFHALLD VARRHDPELE    50
    DVLHGRADIS SFTPEMLARA LQVQGIWFQL VSIAEQNAAM RRRRHVERDQ 100
    GREALNGSFA KVLAEASARG IGPQQIHALL KDLRIRPTIT AHPTEGKRVT 150
    VLEKLRRIYL VLRELELPRW TERERNGLMN ELRDQIELIW MTGELHLEKA 200
    TVEREVAWGL HFFDETLFEM LPEMLLSLEE SLAQYYPDET FEVPPFFQFG 250
    SWIGGDRDGN PYVTASVTRE TLQRNALASL RRYRDGITHL GRVLSITERS 300
    LPVPETFRSE LAHMLAESGD ARAIANRNPG EAYRQFLSCV LRKLKATIAR 350
    NKGARSVGPD YPSADGLIND LRTLEKGLAD AKCGALATDI VRPVRRMVEI 400
    FRFSTVRLDL RENSTRTTKT LHALWKLRNG DREPPALDSP AWKDWLLTEL 450
    ARPRTPETSF EDFADRLPDD ARETLATFAL VGEMRDTLDR EAFGAFILSM 500
    TRSTVDVLGA YLLAKEAGIF LDTTGTEICP LPIVPLFETI DDLRAAPAIM 550
    KELLGIPVVR RSTRWQGGVQ EVMIGYSDSN KDGGFIASNW ELYKAQVRLT 600
    TLGNHLGVPI AFFHGRGGSV SRGGVPTHRG IAAQPPGSIQ GRFRITEQGE 650
    VVSFKYANRG TAAYQMELLA ASVFEHALLS EGNGNGSRAE FDDALEALSG 700
    ASRAAYVNLL QAEGLVDYFQ AASPLDEISL LNIGSRPARR FGAKSLSDLR 750
    AIPWVFAWSQ NRHVITGWYG VGSGLKSFID VRGEAGEALL RRLFRDCRVF 800
    RLVLDEVEKT LLMVDLEIAR DYAGLVEDEG IRARIFGMIE AEYALTREMV 850
    LRVSGDSELA QRFPQFSERL RGRLPTINQV SREQVELLRR YRSETDEDKR 900
    EAVKSALLLS INCIAVGFGA TG 922
    Length:922
    Mass (Da):103,079
    Last modified:February 5, 2008 - v1
    Checksum:i4BD01BCA1C469C7E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000908 Genomic DNA. Translation: ABY30200.1.
    RefSeqiYP_001639271.1. NC_010172.1.

    Genome annotation databases

    EnsemblBacteriaiABY30200; ABY30200; Mext_1801.
    GeneIDi5832923.
    KEGGimex:Mext_1801.
    PATRICi22534095. VBIMetExt98426_1807.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000908 Genomic DNA. Translation: ABY30200.1 .
    RefSeqi YP_001639271.1. NC_010172.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 419610.Mext_1801.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABY30200 ; ABY30200 ; Mext_1801 .
    GeneIDi 5832923.
    KEGGi mex:Mext_1801.
    PATRICi 22534095. VBIMetExt98426_1807.

    Phylogenomic databases

    eggNOGi COG2352.
    HOGENOMi HOG000238647.
    KOi K01595.
    OMAi YNAPIIQ.
    OrthoDBi EOG6TJ7T8.

    Enzyme and pathway databases

    BioCyci MEXT419610:GI32-1841-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PA1Imported.

    Entry informationi

    Entry nameiA9W3P4_METEP
    AccessioniPrimary (citable) accession number: A9W3P4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 5, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3