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A9W387 (A9W387_METEP) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Succinyl-CoA ligase [ADP-forming] subunit beta HAMAP-Rule MF_00558
EC=6.2.1.5 HAMAP-Rule MF_00558
Alternative name(s):
Succinyl-CoA synthetase subunit beta HAMAP-Rule MF_00558
Gene names
Name:sucC HAMAP-Rule MF_00558
Ordered Locus Names:Mext_1644
OrganismMethylobacterium extorquens (strain PA1) [Complete proteome] [HAMAP] EMBL ABY30043.1
Taxonomic identifier419610 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium ›

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. HAMAP-Rule MF_00558 SAAS SAAS013650

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. HAMAP-Rule MF_00558 SAAS SAAS013650

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1. HAMAP-Rule MF_00558 SAAS SAAS013650

Subunit structure

Heterotetramer of two alpha and two beta subunits By similarity. HAMAP-Rule MF_00558 SAAS SAAS013650

Sequence similarities

Belongs to the succinate/malate CoA ligase beta subunit family. RuleBase RU000678 HAMAP-Rule MF_00558

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00558 SAAS SAAS013650

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain9 – 254246ATP-grasp By similarity HAMAP-Rule MF_00558
Nucleotide binding35 – 11884ATP By similarity HAMAP-Rule MF_00558

Sites

Metal binding2071Magnesium or manganese By similarity HAMAP-Rule MF_00558
Metal binding2091Magnesium or manganese By similarity HAMAP-Rule MF_00558

Sequences

Sequence LengthMass (Da)Tools
A9W387 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 770B146BEE68227F

FASTA39841,973
        10         20         30         40         50         60 
MNIHEYQAKA VLKEFGLPVS RGVPIFKPEE AAAAADELGG PVWVVKSQIH AGGRGKGTFK 

        70         80         90        100        110        120 
GAPEGAKGGV RVTKSKDEVV QFAREMLGQT LVTVQTGEAG KQVNRLYIEE GASIAAEFYL 

       130        140        150        160        170        180 
SMLVDRETGR VAFVVSTEGG MDIEQVAHDT PEKIVTFSVD PATGIMPHHG RAVAKALGLS 

       190        200        210        220        230        240 
GPQAKEAGAL TEKLYAAFTA KDMSMLEINP LVLTGDGGLK CLDAKISFDS NALYRHPEIV 

       250        260        270        280        290        300 
ALRDETEEDA KEIEASKYDL AYIALDGTIG CMVNGAGLAM ATLDIIKLYG EEPANFLDVG 

       310        320        330        340        350        360 
GGASEEKVTA AFKIITADPQ VKGILVNIFG GIMKCDVIAR GVIAAVKAVG LEVPLVVRLE 

       370        380        390 
GTNVEEGKEI IRNSGLNVIP ADDLDDAAQK IVAAVKKG

« Hide

References

[1]"Complete sequence of Methylobacterium extorquens PA1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Marx C., Richardson P.
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PA1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000908 Genomic DNA. Translation: ABY30043.1.
RefSeqYP_001639114.1. NC_010172.1.

3D structure databases

ProteinModelPortalA9W387.
SMRA9W387. Positions 1-395.
ModBaseSearch...

Protein-protein interaction databases

STRING419610.Mext_1644.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABY30043; ABY30043; Mext_1644.
GeneID5833000.
KEGGmex:Mext_1644.
PATRIC22533779. VBIMetExt98426_1650.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0045.
HOGENOMHOG000007059.
KOK01903.
OMAQPVTKIL.
ProtClustDBCLSK2330795.

Enzyme and pathway databases

BioCycMEXT419610:GI32-1683-MONOMER.
UniPathwayUPA00223; UER00999.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.261. 1 hit.
HAMAPMF_00558. Succ_CoA_beta.
InterProIPR011761. ATP-grasp.
IPR013650. ATP-grasp_succ-CoA_synth-type.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005811. CoA_ligase.
IPR017866. Succ-CoA_synthase_bsu_CS.
IPR005809. Succ_CoA_synthase_bsu.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PANTHERPTHR11815. PTHR11815. 1 hit.
PfamPF08442. ATP-grasp_2. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFPIRSF001554. SucCS_beta. 1 hit.
SUPFAMSSF52210. CoA_ligase. 1 hit.
TIGRFAMsTIGR01016. sucCoAbeta. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS01217. SUCCINYL_COA_LIG_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9W387_METEP
AccessionPrimary (citable) accession number: A9W387
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info