A9W327 (RSMG_METEP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase G
EC=2.1.1.170

Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase

Gene names

Name:	rsmG
Ordered Locus Names:	Mext_1584

Organism

Methylobacterium extorquens (strain PA1) [Complete proteome] [HAMAP]

Taxonomic identifier

419610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	211 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the N7 position of guanosine in position 527 of 16S rRNA By similarity. HAMAP MF_00074
Catalytic activity	S-adenosyl-L-methionine + guanosine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanosine(527) in 16S rRNA. HAMAP MF_00074
Subcellular location	Cytoplasm Potential HAMAP MF_00074.
Sequence similarities	Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 211	211	Ribosomal RNA small subunit methyltransferase G HAMAP MF_00074		PRO_1000092637

Sequences

	Sequence		Length	Mass (Da)
	A9W327 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 308B0B186D2A0E9F	FASTA	211	22,913
	10 20 30 40 50 60 MSTDLRTHVL SEHHVSRETA ASLDLYVAQL TRWQTVKNLV GPATLKEVWH RHIADALQLL 70 80 90 100 110 120 TVAPEATRWL DLGSGAGIPG LILALAGKER PGFHVGLVES NARKCAFLSE TARLTGAPVT 130 140 150 160 170 180 VHNARIEAVI GTLTDTEIVC ARALAPLSQL LAWTEPLLTS GTIGLFPKGR DAATELTEAE 190 200 210 DEWTFTRDLI PSRTDSQARI VRVTSLSRVD P

References

[1]

"Complete sequence of Methylobacterium extorquens PA1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Marx C., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PA1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000908 Genomic DNA. Translation: ABY29983.1.
RefSeq	YP_001639054.1. NC_010172.1.
3D structure databases
ProteinModelPortal	A9W327.
ModBase	Search...
Protein-protein interaction databases
STRING	A9W327.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5831268.
GenomeReviews	Gene locus Mext_1584 in contig CP000908_GR.
KEGG	mex:Mext_1584.
PATRIC	22533651. VBIMetExt98426_1586.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG686577.
OMA	GGQGWIV.
ProtClustDB	CLSK2330754.
Enzyme and pathway databases
BioCyc	MEXT419610:MEXT_1584-MONOMER.
Family and domain databases
HAMAP	MF_00074. 16SrRNA_methyltr_G. [Tree]
InterPro	IPR003682. rRNA_ssu_MeTfrase_G. [Graphical view]
KO	K03501.
Pfam	PF02527. GidB. 1 hit. [Graphical view]
PIRSF	PIRSF003078. GidB. 1 hit.
TIGRFAMs	TIGR00138. GidB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RSMG_METEP

Accession

Primary (citable) accession number: A9W327

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program