A9W2W7 (A9W2W7_METEP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut EMBL ABY29923.1

Gene names

Ordered Locus Names:

Mext_1524

Organism

Methylobacterium extorquens (strain PA1) [Complete proteome] [HAMAP]

Taxonomic identifier

419610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA By similarity. SAAS SAAS008181
Cofactor	Magnesium By similarity. SAAS SAAS008181

Ontologies

Keywords
Biological process	Nucleotide metabolism SAAS SAAS008181
Ligand	Magnesium SAAS SAAS008181
Molecular function	Hydrolase SAAS SAAS008181 EMBL ABY29923.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	dUTP diphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9W2W7 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 255A31BF9165ED40	FASTA	168	17,397
	10 20 30 40 50 60 MSQSPSKVGL HILDPRLAGW GFPRWGSIAA AGLDLHACLD APLVLEPQAP PALIPAGFSL 70 80 90 100 110 120 RIGESDWCGL VFARSGLGHR EGLVLGNGTG VIDADYEGPL LISAWNRNPP GSGAAIRIEP 130 140 150 160 GERIAQLVFT RVLRPDFEIC DGAPEPNGPG GGGQGSRGQG GFGSTGRR

References

[1]

"Complete sequence of Methylobacterium extorquens PA1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Marx C., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PA1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000908 Genomic DNA. Translation: ABY29923.1.
RefSeq	YP_001638994.1. NC_010172.1.
3D structure databases
ProteinModelPortal	A9W2W7.
ModBase	Search...
Protein-protein interaction databases
STRING	A9W2W7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5832580.
GenomeReviews	Gene locus Mext_1524 in contig CP000908_GR.
KEGG	mex:Mext_1524.
PATRIC	22533529. VBIMetExt98426_1525.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG436079.
OMA	LDLRACI.
ProtClustDB	CLSK2330713.
Family and domain databases
InterPro	IPR008180. dUTP_pyroPase. IPR008181. dUTP_pyroPase_sf. [Graphical view]
KO	K01520.
PANTHER	PTHR11241. PTHR11241. 1 hit.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9W2W7_METEP

Accession

Primary (citable) accession number: A9W2W7

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)