A9W0H9 (A9W0H9_METEP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Coproporphyrinogen oxidase EMBL ABY29085.1
EC=1.3.3.3 EMBL ABY29085.1

Gene names

Ordered Locus Names:

Mext_0673

Organism

Methylobacterium extorquens (strain PA1) [Complete proteome] [HAMAP]

Taxonomic identifier

419610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III By similarity. SAAS SAAS018375
Catalytic activity	Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. SAAS SAAS018375
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. SAAS SAAS018375
Subunit structure	Homodimer By similarity. SAAS SAAS018375

Ontologies

Keywords
Biological process	Porphyrin biosynthesis SAAS SAAS018375
Molecular function	Oxidoreductase SAAS SAAS018375 EMBL ABY29085.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9W0H9 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 3FA028F60356DB6C	FASTA	307	34,190
	10 20 30 40 50 60 MSDATASPLP SPDDLAALKS EAGAWFSTLR DRIVTALETL EAEATGPFHP DAPKEAGTFE 70 80 90 100 110 120 KTPWQRTDHS GTPGGGGVMA MLKGRVFEKA GVHISTVHGE FAPEFRAQMP GAAEDPRFFA 130 140 150 160 170 180 TGISLIVHPW NPNVPTVHMN TRFVVTTKAW FGGGADLTPV LDRRRTQEDP DTQFFHACLR 190 200 210 220 230 240 EACEKHAPAA DYEKYKAWCD EYFHLKHRNE PRGIGGIFYD YHWTGDPQAD LAYTRDVGGA 250 260 270 280 290 300 FLKAYPEIVR RNLAQAWTEA DREEQQVRRG RYVEFNLLYD RGTIFGLKTG GNVASILSSL PPTVRWP

References

[1]

"Complete sequence of Methylobacterium extorquens PA1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Marx C., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PA1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000908 Genomic DNA. Translation: ABY29085.1.
RefSeq	YP_001638156.1. NC_010172.1.
3D structure databases
ProteinModelPortal	A9W0H9.
ModBase	Search...
Protein-protein interaction databases
STRING	A9W0H9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5835211.
GenomeReviews	Gene locus Mext_0673 in contig CP000908_GR.
KEGG	mex:Mext_0673.
PATRIC	22531701. VBIMetExt98426_0641.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG631180.
OMA	VKAYLLD.
ProtClustDB	PRK05330.
Family and domain databases
InterPro	IPR001260. Coprogen_oxidase_aer. IPR018375. Coprogen_oxidase_CS. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
KO	K00228.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
SUPFAM	SSF102886. Coprogen_oxidas. 1 hit.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9W0H9_METEP

Accession

Primary (citable) accession number: A9W0H9

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)