A9VYZ2 (RPOZ_METEP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit omega
Short name=RNAP omega subunit
EC=2.7.7.6

Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega

Gene names

Name:	rpoZ
Ordered Locus Names:	Mext_3197

Organism

Methylobacterium extorquens (strain PA1) [Complete proteome] [HAMAP]

Taxonomic identifier

419610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	136 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity. HAMAP MF_00366
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00366
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.
Sequence similarities	Belongs to the RNA polymerase subunit omega family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	RNA polymerase complex Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 136	136	DNA-directed RNA polymerase subunit omega HAMAP MF_00366		PRO_1000121244

Sequences

	Sequence		Length	Mass (Da)
	A9VYZ2 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 096751BF3AD0AAE3	FASTA	136	14,990
	10 20 30 40 50 60 MARVTVEDCI EKVENRFELV LLASHRARLL AAGAPLTVER DRDKNPVVAL REIGDETITA 70 80 90 100 110 120 EDLKEQLIHS MQKYVEVDEP EAETVPLLSS SPAAAAVAPQ SSSDDKNVQF DFMSEEDLLR 130 GLENLAPPTE TDDEGE

References

[1]

"Complete sequence of Methylobacterium extorquens PA1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Marx C., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PA1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000908 Genomic DNA. Translation: ABY31584.1.
RefSeq	YP_001640655.1. NC_010172.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A9VYZ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5832918.
GenomeReviews	Gene locus Mext_3197 in contig CP000908_GR.
KEGG	mex:Mext_3197.
PATRIC	22536984. VBIMetExt98426_3239.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG742204.
OMA	KVDNRFE.
ProtClustDB	PRK00392.
Enzyme and pathway databases
BioCyc	MEXT419610:MEXT_3197-MONOMER.
Family and domain databases
HAMAP	MF_00366. RNApol_bact_RpoZ. [Tree]
InterPro	IPR003716. DNA-dir_RNA_pol_omega. IPR006110. RNA_poly_omega/K/RPABC2. IPR012293. RNAP_RPB6_omega. [Graphical view]
Gene3D	G3DSA:3.90.940.10. RNAP_RPB6_omega. 1 hit.
KO	K03060.
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
SUPFAM	SSF63562. RNA_pol_omega. 1 hit.
TIGRFAMs	TIGR00690. RpoZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPOZ_METEP

Accession

Primary (citable) accession number: A9VYZ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program