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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Methylobacterium extorquens (strain PA1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi8Divalent metal cationUniRule annotation1
Metal bindingi9Divalent metal cationUniRule annotation1
Metal bindingi40Divalent metal cationUniRule annotation1
Metal bindingi93Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:Mext_4233
OrganismiMethylobacterium extorquens (strain PA1)
Taxonomic identifieri419610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000008546 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000920161 – 2545'-nucleotidase SurEAdd BLAST254

Interactioni

Protein-protein interaction databases

STRINGi419610.Mext_4233.

Structurei

3D structure databases

ProteinModelPortaliA9VY48.
SMRiA9VY48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiDCVHIAL.
OrthoDBiPOG091H01CP.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiView protein in InterPro
IPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
IPR036523. SurE-like_sf.
PfamiView protein in Pfam
PF01975. SurE. 1 hit.
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

A9VY48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILVTNDDG IHAPGLETLE GIARALSDDV WVVAPETDQS GVSHSLSLND
60 70 80 90 100
PLRLRQIGEK RFAVKGTPSD CIIMGVAHIL KDHKPDLVLS GVNRGQNVAE
110 120 130 140 150
DVTYSGTIAG AMEGTILGIR SIALSQAYGA GGRANLKWAC AATHGPRVIE
160 170 180 190 200
KILEIGIEPG ILVNVNFPDC EPEDVQGVAV SAQGQRNQAL LQIDARHDGR
210 220 230 240 250
GNPYFWLAFA KARFEPGNGT DLKAIAENRI SVTPLRLDLT DEPELTRFAA

AFRA
Length:254
Mass (Da):27,263
Last modified:February 5, 2008 - v1
Checksum:iCAC19AE3A66E2589
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000908 Genomic DNA. Translation: ABY32602.1.
RefSeqiWP_003605704.1. NC_010172.1.

Genome annotation databases

EnsemblBacteriaiABY32602; ABY32602; Mext_4233.
KEGGimex:Mext_4233.

Similar proteinsi

Entry informationi

Entry nameiSURE_METEP
AccessioniPrimary (citable) accession number: A9VY48
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: October 25, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families