A9VUC4 (TGL_BACWK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-glutamine gamma-glutamyltransferase
EC=2.3.2.13

Alternative name(s):
Transglutaminase
Short name=TGase

Gene names

Name:	tgl
Ordered Locus Names:	BcerKBAB4_3789

Organism

Bacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP]

Taxonomic identifier

315730 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › Bacillus weihenstephanensis

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links By similarity. HAMAP-Rule MF_00727
Catalytic activity	Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3. HAMAP-Rule MF_00727
Sequence similarities	Belongs to the bacillus TGase family.

Ontologies

Keywords
Biological process	Sporulation
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: HAMAP
Molecular_function	protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	Protein-glutamine gamma-glutamyltransferase HAMAP-Rule MF_00727		PRO_1000197971

Sequences

	Sequence		Length	Mass (Da)
	A9VUC4 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: DEB0A7EC5051D765	FASTA	276	31,590
	10 20 30 40 50 60 MIVIGRSIVH PYITNEYEPF AAEKQQILSI MAGNQEVYSF RTADELSFDL NLRVNIITSA 70 80 90 100 110 120 LELFQSGFQF RTFQQSFCNP QFWERTSLGG FQLLPNIAPS IAIQDIFKNG KLYGTECATA 130 140 150 160 170 180 MIIIFYKALL SLYEEKTFNR LFANLLLYTW DYDRDLKLIT KTSGDIVPGD LVYFKNPQVN 190 200 210 220 230 240 PATIEWQGEN AIYLGNFFFY GHGVGVKTKE EIIYSLNERR IPYAFISAYL TDFITRIDSR 250 260 270 MMSQYAPPNT PQTSIGFIPI RDDAIVATVG HTTTIY

References

[1]

"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity." Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A. Chem. Biol. Interact. 171:236-249(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KBAB4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000903 Genomic DNA. Translation: ABY44958.1.
RefSeq	YP_001646586.1. NC_010184.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	315730.BcerKBAB4_3789.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABY44958; ABY44958; BcerKBAB4_3789.
GeneID	5844001.
KEGG	bwe:BcerKBAB4_3789.
PATRIC	19012215. VBIBacWei55973_4424.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG12337.
HOGENOM	HOG000262157.
KO	K00686.
OMA	FECATAI.
ProtClustDB	PRK03187.
Enzyme and pathway databases
BioCyc	BWEI315730:GHRU-3904-MONOMER.
Family and domain databases
HAMAP	MF_00727. Tgl.
InterPro	IPR020916. Gln_gamma-glutamylTfrase_bac. [Graphical view]
ProDom	PD119415. PD119415. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

TGL_BACWK

Accession

Primary (citable) accession number: A9VUC4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program