A9VT88 (ACP_BACWK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acyl carrier protein
Short name=ACP

Gene names

Name:	acpP
Ordered Locus Names:	BcerKBAB4_3673

Organism

Bacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP]

Taxonomic identifier

315730 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	77 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Carrier of the growing fatty acid chain in fatty acid biosynthesis By similarity. HAMAP MF_01217
Pathway	Lipid metabolism; fatty acid biosynthesis. HAMAP MF_01217
Subcellular location	Cytoplasm By similarity HAMAP MF_01217.
Post-translational modification	4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity. HAMAP MF_01217
Sequence similarities	Contains 1 acyl carrier domain.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Ligand	Phosphopantetheine
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 77	77	Acyl carrier protein HAMAP MF_01217		PRO_1000139002
Amino acid modifications
	Modified residue	37	1	O-(pantetheine 4'-phosphoryl)serine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9VT88 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 8CD8BE2AF75830AB	FASTA	77	8,498
	10 20 30 40 50 60 MADVLERVTK IVVDRLGVEE TEVVPAASFK EDLGADSLDV VELVMQLEDE FEMEISDEDA 70 EKIATVGDAV TYIESHL

References

[1]

"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity." Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A. Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KBAB4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000903 Genomic DNA. Translation: ABY44844.1.
RefSeq	YP_001646472.1. NC_010184.1.
3D structure databases
ProteinModelPortal	A9VT88.
SMR	A9VT88. Positions 2-76.
ModBase	Search...
Protein-protein interaction databases
STRING	A9VT88.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000078443; EBBACP00000076377; EBBACG00000078434.
GeneID	5843885.
GenomeReviews	Gene locus BcerKBAB4_3673 in contig CP000903_GR.
KEGG	bwe:BcerKBAB4_3673.
PATRIC	19011983. VBIBacWei55973_4308.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000002064.
HOGENOM	HBG755218.
OMA	IDYVNSH.
ProtClustDB	PRK00982.
Enzyme and pathway databases
BioCyc	BWEI315730:BCERKBAB4_3673-MONOMER.
Family and domain databases
HAMAP	MF_01217. Acyl_carrier. [Tree]
InterPro	IPR003231. Acyl_carrier. IPR009081. Acyl_carrier_prot-like. IPR006163. Phsphopanteth-bd. IPR006162. PPantetheine_attach_site. [Graphical view]
Gene3D	G3DSA:1.10.1200.10. ACP_like. 1 hit.
KO	K02078.
Pfam	PF00550. PP-binding. 1 hit. [Graphical view]
ProDom	PD000887. PD000887. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF47336. ACP_like. 1 hit.
TIGRFAMs	TIGR00517. Acyl_carrier. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACP_BACWK

Accession

Primary (citable) accession number: A9VT88

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program