Skip Header

Contribute Send feedback
Read comments (?) or add your own

A9VSD2 (A9VSD2_BACWK) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase HAMAP-Rule MF_00111
EC=2.5.1.7 HAMAP-Rule MF_00111
Alternative name(s):
Enoylpyruvate transferase HAMAP-Rule MF_00111
UDP-N-acetylglucosamine enolpyruvyl transferase HAMAP-Rule MF_00111
Gene names
Name:murA HAMAP-Rule MF_00111
Ordered Locus Names:BcerKBAB4_5132 EMBL ABY46278.1
OrganismBacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP] EMBL ABY46278.1
Taxonomic identifier315730 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group ›

Protein attributes

Sequence length429 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. HAMAP-Rule MF_00111 SAAS SAAS005750

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine. HAMAP-Rule MF_00111 SAAS SAAS005750

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00111

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00111 SAAS SAAS005750.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily. HAMAP-Rule MF_00111

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1171Proton donor By similarity HAMAP-Rule MF_00111

Amino acid modifications

Modified residue11712-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity HAMAP-Rule MF_00111

Sequences

Sequence LengthMass (Da)Tools
A9VSD2 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: C8C6DB85C836B536

FASTA42945,923
        10         20         30         40         50         60 
MEKLLIEGGR ALNGTIRVSG AKNSAVALIP ATILADTPVT IGGVPNISDV KMLGDLLEEI 

        70         80         90        100        110        120 
GGKVTYGQEE EMVVDPSNMV AMPLPNGKVK KLRASYYLMG AMLGRFKKAV IGLPGGCHLG 

       130        140        150        160        170        180 
PRPIDQHIKG FEALGAYVTN EQGAIYLRAD ELRGARIYLD VVSVGATINI MLVAVRAKGR 

       190        200        210        220        230        240 
TVIENAAKEP EIIDVATLLT SMGARIKGAG TDVIRIDGVD SLHGCHHTII PDRIEAGTYM 

       250        260        270        280        290        300 
ILGAASGGEV TVDNVIPQHL ESVTAKLREA GVQIETNDDQ ITVNGNRRLK VVDVKTLVYP 

       310        320        330        340        350        360 
GFPTDLQQPF TTLLTKAHGT GVVTDTIYSA RFKHIDELRR MNAQIKVEGR SAIVTGPVLL 

       370        380        390        400        410        420 
QGAKVKASDL RAGASLVIAG LMADGITEVT GLDHIDRGYE NIVDKLKGLG ANIWREQMTK 


QEIEEMKNA

« Hide

References

[1]"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity."
Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.H., Sanchis V., Nguen-The C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A.
Chem. Biol. Interact. 171:236-249(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KBAB4 EMBL ABY46278.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000903 Genomic DNA. Translation: ABY46278.1.
RefSeqYP_001647906.1. NC_010184.1.

3D structure databases

ProteinModelPortalA9VSD2.
ModBaseSearch...

Protein-protein interaction databases

STRING315730.BcerKBAB4_5132.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABY46278; ABY46278; BcerKBAB4_5132.
GeneID5845373.
KEGGbwe:BcerKBAB4_5132.
PATRIC19015019. VBIBacWei55973_5796.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0766.
HOGENOMHOG000075602.
KOK00790.
OMAEHTMLPD.
ProtClustDBPRK12830.

Enzyme and pathway databases

BioCycBWEI315730:GHRU-5276-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00111. MurA.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01072. murA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA9VSD2_BACWK
AccessionPrimary (citable) accession number: A9VSD2
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info