A9VRE5 (A9VRE5_BACWK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
N5-carboxyaminoimidazole ribonucleotide mutase PIRNR PIRNR001338
Short name=N5-CAIR mutase PIRNR PIRNR001338
EC=5.4.99.18 PIRNR PIRNR001338

Gene names

Ordered Locus Names:

BcerKBAB4_0269 EMBL ABY41535.1

Organism

Bacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP] EMBL ABY41535.1

Taxonomic identifier

315730 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › Bacillus weihenstephanensis

Protein attributes

Sequence length	161 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) By similarity. PIRNR PIRNR001338
Catalytic activity	5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. PIRNR PIRNR001338
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2. PIRNR PIRNR001338
Sequence similarities	Belongs to the AIR carboxylase family. PIRNR PIRNR001338

Ontologies

Keywords
Biological process	Purine biosynthesis PIRNR PIRNR001338
Molecular function	Isomerase PIRNR PIRNR001338 Lyase EMBL ABY41535.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	5-(carboxyamino)imidazole ribonucleotide mutase activity Inferred from electronic annotation. Source: EC lyase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Binding site	11	1	Substrate By similarity PIRSR PIRSR001338-1
	Binding site	14	1	Substrate By similarity PIRSR PIRSR001338-1
	Binding site	41	1	Substrate By similarity PIRSR PIRSR001338-1

Sequences

	Sequence		Length	Mass (Da)
	A9VRE5 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 7F92A80C2A91A94E	FASTA	161	17,028
	10 20 30 40 50 60 MKSLVGVIMG STSDWETMKY ACDILDELNI PYEKKVVSAH RTPDYMFEYA ETARERGLKV 70 80 90 100 110 120 IIAGAGGAAH LPGMVAAKTN LPVIGVPVQS KALNGLDSLL SIVQMPGGVP VATVAIGKAG 130 140 150 160 STNAGLLAAQ ILGSFHDDIH DALELRREAI EKTVREGSEL V

References

[1]

"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity." Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.H., Sanchis V., Nguen-The C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A. Chem. Biol. Interact. 171:236-249(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KBAB4 EMBL ABY41535.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000903 Genomic DNA. Translation: ABY41535.1.
RefSeq	YP_001643163.1. NC_010184.1.
3D structure databases
ProteinModelPortal	A9VRE5.
SMR	A9VRE5. Positions 2-161.
ModBase	Search...
Protein-protein interaction databases
STRING	315730.BcerKBAB4_0269.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABY41535; ABY41535; BcerKBAB4_0269.
GeneID	5840439.
KEGG	bwe:BcerKBAB4_0269.
PATRIC	19004938. VBIBacWei55973_0833.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0041.
HOGENOM	HOG000034141.
KO	K01588.
OMA	QSDWATM.
ProtClustDB	CLSK915770.
Enzyme and pathway databases
BioCyc	BWEI315730:GHRU-342-MONOMER.
UniPathway	UPA00074; UER00943.
Family and domain databases
Gene3D	3.40.50.7700. 1 hit.
InterPro	IPR024694. N5-CAIR_mutase_PurE. IPR000031. N5-CAIR_Mutase_PurE_dom. [Graphical view]
Pfam	PF00731. AIRC. 1 hit. [Graphical view]
PIRSF	PIRSF001338. AIR_carboxylase. 1 hit.
SMART	SM01001. AIRC. 1 hit. [Graphical view]
SUPFAM	SSF52255. AIR_carboxyl. 1 hit.
TIGRFAMs	TIGR01162. purE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9VRE5_BACWK

Accession

Primary (citable) accession number: A9VRE5

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)