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Protein

Pyrophosphatase PpaX

Gene

ppaX

Organism
Bacillus weihenstephanensis (strain KBAB4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.UniRule annotation

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei9 – 91NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciBWEI315730:GHRU-5099-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrophosphatase PpaXUniRule annotation (EC:3.6.1.1UniRule annotation)
Gene namesi
Name:ppaXUniRule annotation
Ordered Locus Names:BcerKBAB4_4954
OrganismiBacillus weihenstephanensis (strain KBAB4)
Taxonomic identifieri315730 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000002154 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 215215Pyrophosphatase PpaXPRO_1000139927Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315730.BcerKBAB4_4954.

Structurei

3D structure databases

ProteinModelPortaliA9VQ75.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PpaX family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108VXP. Bacteria.
COG0546. LUCA.
HOGENOMiHOG000248344.
KOiK06019.
OMAiHAEEMRV.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 1 hit.
HAMAPiMF_01250. Pyrophosphat_PpaX. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR006549. HAD-SF_hydro_IIIA.
IPR023198. PGP_dom2.
IPR023733. Pyrophosphatase_Ppax.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
PRINTSiPR00413. HADHALOGNASE.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01549. HAD-SF-IA-v1. 1 hit.
TIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01662. HAD-SF-IIIA. 1 hit.

Sequencei

Sequence statusi: Complete.

A9VQ75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKINTVLFDL DGTLINTNEL IISSFLHTLN HYYSNQYKRE DVLPFIGPSL
60 70 80 90 100
HDTFSKIDAS KVEEMITCYR QFNHEHHDEL VEEYETVYET VQELKKQGYK
110 120 130 140 150
IGIVTTKARQ TVEMGLKLSK LDQFFDVVVT IDDVEHVKPH PEPLQKALEL
160 170 180 190 200
LDAKPEETLM VGDNHHDIVG GQNAGTKTVA VSWTLKGRAY LEAYKPDYVL
210
DKMSDLLPIL SRING
Length:215
Mass (Da):24,607
Last modified:February 5, 2008 - v1
Checksum:iA1E307E74D95D9AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000903 Genomic DNA. Translation: ABY46102.1.
RefSeqiWP_002112826.1. NC_010184.1.

Genome annotation databases

EnsemblBacteriaiABY46102; ABY46102; BcerKBAB4_4954.
KEGGibwe:BcerKBAB4_4954.
PATRICi19014651. VBIBacWei55973_5612.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000903 Genomic DNA. Translation: ABY46102.1.
RefSeqiWP_002112826.1. NC_010184.1.

3D structure databases

ProteinModelPortaliA9VQ75.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi315730.BcerKBAB4_4954.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABY46102; ABY46102; BcerKBAB4_4954.
KEGGibwe:BcerKBAB4_4954.
PATRICi19014651. VBIBacWei55973_5612.

Phylogenomic databases

eggNOGiENOG4108VXP. Bacteria.
COG0546. LUCA.
HOGENOMiHOG000248344.
KOiK06019.
OMAiHAEEMRV.

Enzyme and pathway databases

BioCyciBWEI315730:GHRU-5099-MONOMER.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 1 hit.
HAMAPiMF_01250. Pyrophosphat_PpaX. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR006549. HAD-SF_hydro_IIIA.
IPR023198. PGP_dom2.
IPR023733. Pyrophosphatase_Ppax.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
PRINTSiPR00413. HADHALOGNASE.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01549. HAD-SF-IA-v1. 1 hit.
TIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01662. HAD-SF-IIIA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPPAX_BACWK
AccessioniPrimary (citable) accession number: A9VQ75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.