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Protein

Pyrophosphatase PpaX

Gene

ppaX

Organism
Bacillus weihenstephanensis (strain KBAB4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.UniRule annotation

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei9NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrophosphatase PpaXUniRule annotation (EC:3.6.1.1UniRule annotation)
Gene namesi
Name:ppaXUniRule annotation
Ordered Locus Names:BcerKBAB4_4954
OrganismiBacillus weihenstephanensis (strain KBAB4)
Taxonomic identifieri315730 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000002154 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001399271 – 215Pyrophosphatase PpaXAdd BLAST215

Interactioni

Protein-protein interaction databases

STRINGi315730.BcerKBAB4_4954

Structurei

3D structure databases

ProteinModelPortaliA9VQ75
SMRiA9VQ75
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PpaX family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108VXP Bacteria
COG0546 LUCA
HOGENOMiHOG000248344
KOiK06019
OMAiLLIFDWD

Family and domain databases

Gene3Di1.10.150.240, 1 hit
3.40.50.1000, 2 hits
HAMAPiMF_01250 Pyrophosphat_PpaX, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR006549 HAD-SF_hydro_IIIA
IPR023214 HAD_sf
IPR023198 PGP-like_dom2
IPR023733 Pyrophosphatase_Ppax
PRINTSiPR00413 HADHALOGNASE
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01549 HAD-SF-IA-v1, 1 hit
TIGR01509 HAD-SF-IA-v3, 1 hit
TIGR01662 HAD-SF-IIIA, 1 hit

Sequencei

Sequence statusi: Complete.

A9VQ75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKINTVLFDL DGTLINTNEL IISSFLHTLN HYYSNQYKRE DVLPFIGPSL
60 70 80 90 100
HDTFSKIDAS KVEEMITCYR QFNHEHHDEL VEEYETVYET VQELKKQGYK
110 120 130 140 150
IGIVTTKARQ TVEMGLKLSK LDQFFDVVVT IDDVEHVKPH PEPLQKALEL
160 170 180 190 200
LDAKPEETLM VGDNHHDIVG GQNAGTKTVA VSWTLKGRAY LEAYKPDYVL
210
DKMSDLLPIL SRING
Length:215
Mass (Da):24,607
Last modified:February 5, 2008 - v1
Checksum:iA1E307E74D95D9AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000903 Genomic DNA Translation: ABY46102.1
RefSeqiWP_002112826.1, NC_010184.1

Genome annotation databases

EnsemblBacteriaiABY46102; ABY46102; BcerKBAB4_4954
KEGGibwe:BcerKBAB4_4954

Similar proteinsi

Entry informationi

Entry nameiPPAX_BACWK
AccessioniPrimary (citable) accession number: A9VQ75
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: March 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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