Reviewed, UniProtKB/Swiss-Prot A9VPC3 (GLMM_BACWK)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BcerKBAB4_0151

Organism

Bacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP]

Taxonomic identifier

315730 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 448	448	Phosphoglucosamine mutase HAMAP MF_01554		PRO_1000201062
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	240	1	Magnesium By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9VPC3-1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: F7A65942A25FF861	FASTA	448	48,358
	10 20 30 40 50 60 MGKYFGTDGV RGVANKELTP ELAFKIGRFG GYVLTKDTDR PKVIIGRDTR VSGHMLEGAL 70 80 90 100 110 120 VAGLLSTGAE VMRLGVISTP GVAYLTKALG AQAGVMISAS HNPVQDNGIK FFGSDGFKLT 130 140 150 160 170 180 DEQEAEIEAL LDKEVDELPR PTGTNLGQVS DYFEGGQKYL QYIKQTVEED FSGLHIALDC 190 200 210 220 230 240 AHGATSSLAP YLFADLEADI STMGTSPNGM NINAGVGSTH PEVLAELVKE KGADIGLAFD 250 260 270 280 290 300 GDGDRLIAVD EKGNIVDGDQ IMFICAKYMK ETGQLKHNTV VSTVMSNLGF YKALEANNIT 310 320 330 340 350 360 SDKTAVGDRY VMEEMKRGGY NLGGEQSGHI ILLDYITTGD GMLSALQLVN IMKMTKKPLS 370 380 390 400 410 420 ELAGEMTKFP QLLVNVRVTD KKLALENEKI KEIIRVVEEE MNGDGRILVR PSGTEPLIRV 430 440 MAEAPTQEIC DGYVHRIVEV VKAEVGAE

References

[1]

"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity." Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A. Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000903 Genomic DNA. Translation: ABY41420.1.
RefSeq	YP_001643048.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5840175.
GenomeReviews	Gene locus BcerKBAB4_0151 in contig CP000903_GR.
KEGG	bwe:BcerKBAB4_0151.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NTIPEDL.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BACWK

Accession

Primary (citable) accession number: A9VPC3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 5, 2008
Last modified:	November 3, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)