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A9VKE9 (ACKA_BACWK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:BcerKBAB4_4468
OrganismBacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP]
Taxonomic identifier315730 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Acetate kinase HAMAP MF_00020
PRO_1000089959

Sequences

Sequence LengthMass (Da)Tools
A9VKE9 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: B05C6E161E73BE04

FASTA39743,190
        10         20         30         40         50         60 
MSKIIAINAG SSSLKFQLFE MPSETVLTKG LVERIGLEDS IFTITVNGEK QKEITNIPDH 

        70         80         90        100        110        120 
AVAVNMLLKK LTENGIVKSL DEIGGIGHRV VHGGEKFADS VLIDAEVLAD IEELSDLAPL 

       130        140        150        160        170        180 
HNPANLVGIK AFQEVLPNVP AVAVFDTAFH QTMPESAFLY SLPYEYYEKF GIRKYGFHGT 

       190        200        210        220        230        240 
SHKYVTERAA ELLGRPIESL SLLSCHLGNG ASIAAVEGGK SIDTSMGFTP LAGVTMGTRS 

       250        260        270        280        290        300 
GNIDPALIPY IMEKTGQTVE EVVSVLNKKS GMLGLTGYSS DLRDIIAKEE EGDHRAKVAL 

       310        320        330        340        350        360 
DVFVSRIHKY IGSYTARMKG VDAIIFTAGV GENSAIIRER VLEGLEYMGV YFDVKRNNVF 

       370        380        390 
GEEAFISFPH SPVKIIVIPT DEEVMIARDV LRLGDIG

« Hide

References

[1]"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity."
Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A.
Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KBAB4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000903 Genomic DNA. Translation: ABY45626.1.
RefSeqYP_001647254.1. NC_010184.1.

3D structure databases

ProteinModelPortalA9VKE9.
SMRA9VKE9. Positions 3-394.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9VKE9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000078419; EBBACP00000076353; EBBACG00000078410.
GeneID5844683.
GenomeReviewsGene locus BcerKBAB4_4468 in contig CP000903_GR.
KEGGbwe:BcerKBAB4_4468.
PATRIC19013610. VBIBacWei55973_5118.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000000769.
HOGENOMHBG285863.
OMALIDMTNE.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycBWEI315730:BCERKBAB4_4468-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BACWK
AccessionPrimary (citable) accession number: A9VKE9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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