A9VJG1 (MQO_BACWK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	BcerKBAB4_2768

Organism

Bacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP]

Taxonomic identifier

315730 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000099868

Sequences

	Sequence		Length	Mass (Da)
	A9VJG1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: C09ABBEBCA892FFE	FASTA	500	55,222
	10 20 30 40 50 60 MSNMQQKTDV ILIGAGIMSA TLGSLLKELA PEWEIKVFEK LANAGEESSN EWNNAGTGHS 70 80 90 100 110 120 ALCELNYTSE KSDGSIDIGK AVKVNEQFQL SRQFWAYLVK RNLIRNPQDF IMPLPHMSLV 130 140 150 160 170 180 QGEKNVEFLK KRFEALSKNA LFQGMEFADA PDTLKKWLPL IMEGRNSNEP MAATKIDSGT 190 200 210 220 230 240 DVNFGALTRM LFDYLKTKNV ELNYKHSVEN IKRAKNGLWE VKVHDMNSGK IEHHTAKFVF 250 260 270 280 290 300 IGGGGGSLPL LQKTGIPESK HIGGFPVSGL FMVCKNQKIV EQHHAKVYGK AKVGAPPMSV 310 320 330 340 350 360 PHLDTRYIDN KKALLFGPFA GFSPKFLKTG SNLDLIGSVK PNNVLTMLAA GVKEMGLTKY 370 380 390 400 410 420 LIQQVMLSHE KRMEELREFI PNAKSEDWDT VVAGQRVQVI KDTDAGGKGT LQFGTEVVSA 430 440 450 460 470 480 NDGSIAALLG ASPGASTAVH VMLEVLEKCF PERILEWEPK IKEMVPSYGV SLTENPRLFQ 490 500 ELHASTGRTL GLNEKEAVHN

References

[1]

"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity." Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A. Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KBAB4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000903 Genomic DNA. Translation: ABY43968.1.
RefSeq	YP_001645596.1. NC_010184.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A9VJG1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000081538; EBBACP00000079472; EBBACG00000081529.
GeneID	5842980.
GenomeReviews	Gene locus BcerKBAB4_2768 in contig CP000903_GR.
KEGG	bwe:BcerKBAB4_2768.
PATRIC	19010141. VBIBacWei55973_3387.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000004051.
HOGENOM	HBG289663.
OMA	KKWVPLM.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	BWEI315730:BCERKBAB4_2768-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_BACWK

Accession

Primary (citable) accession number: A9VJG1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program