Skip Header

Contribute Send feedback
Read comments (?) or add your own

A9VHW5 (PSD_BACWK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:BcerKBAB4_4189
OrganismBacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP]
Taxonomic identifier315730 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length262 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 225225Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000131348
Chain226 – 26237Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000131349

Sites

Site225 – 2262Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2261Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
A9VHW5 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 33E8D90AFA503CA7

FASTA26229,784
        10         20         30         40         50         60 
MRRTLYRLMI ELTNGRFTSY ILRKFAQSRL SSIIIPSYVK VFQINQDEME KGLKEYGTLH 

        70         80         90        100        110        120 
DLFTRRLKEG KRSIDTDASS IVSPVDGVFA DQGPIEDTKT FDIKGKRYSI VDMLGNEERA 

       130        140        150        160        170        180 
KRYAGGTYMV IYLSPSHYHR IHSPLSGSVT ERFVLGRKSY PVNAAGMEYG KEPLSKNYRS 

       190        200        210        220        230        240 
VTEVNSDGEH MALVKVGAMF INSIELLHER STVQKGEEMA YFTFGSTVVL LFEKDMIKAV 

       250        260 
QELTSGQELR LGEKIATRVS HK

« Hide

References

[1]"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity."
Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A.
Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KBAB4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000903 Genomic DNA. Translation: ABY45350.1.
RefSeqYP_001646978.1. NC_010184.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA9VHW5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000079975; EBBACP00000077909; EBBACG00000079966.
GeneID5844402.
GenomeReviewsGene locus BcerKBAB4_4189 in contig CP000903_GR.
KEGGbwe:BcerKBAB4_4189.
PATRIC19013042. VBIBacWei55973_4836.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000001988.
HOGENOMHBG302256.
OMANKREWSI.
ProtClustDBPRK03140.

Enzyme and pathway databases

BioCycBWEI315730:BCERKBAB4_4189-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BACWK
AccessionPrimary (citable) accession number: A9VHW5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents