A9VG70 (ARGB_BACWK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetylglutamate kinase
EC=2.7.2.8

Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK

Gene names

Name:	argB
Ordered Locus Names:	BcerKBAB4_3963

Organism

Bacillus weihenstephanensis (strain KBAB4) [Complete proteome] [HAMAP]

Taxonomic identifier

315730 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00082_B.
Sequence similarities	Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	Acetylglutamate kinase HAMAP MF_00082_B		PRO_1000092847
Regions
	Region	40 – 41	2	Substrate binding By similarity
Sites
	Binding site	62	1	Substrate By similarity
	Binding site	153	1	Substrate By similarity
	Site	8	1	Transition state stabilizer By similarity
	Site	212	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	A9VG70 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 3C3FFE55494E73EB	FASTA	255	27,444
	10 20 30 40 50 60 MSDYIVVKCG GSMLDQLNDV FFDCIKKLQQ KYKVVIVHGG GPEIDAKLKD CNIKVEKRDG 70 80 90 100 110 120 LRVTPREVMD IVQMVLCGST NKKLVMNLQK HNLLAVGCSG CDGNLLQVQP VSKEIGYVGE 130 140 150 160 170 180 VSYVETALLK GLINMNYIPV IAPIGINENE IYNINADNAA AGIAAALSAK ELIFITDVDG 190 200 210 220 230 240 ILHEGKLVKK TDEFEIDTFI EKGVITGGMI PKVQAALASL KMGVQKVSVV NGTKDFAEVT 250 GECIGTTVTK GVNIV

References

[1]

"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity." Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A. Chem. Biol. Interact. 171:236-249(2008) [PubMed: 17434157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KBAB4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000903 Genomic DNA. Translation: ABY45130.1.
RefSeq	YP_001646758.1. NC_010184.1.
3D structure databases
ProteinModelPortal	A9VG70.
ModBase	Search...
Protein-protein interaction databases
STRING	A9VG70.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000077693; EBBACP00000075627; EBBACG00000077684.
GeneID	5844175.
GenomeReviews	Gene locus BcerKBAB4_3963 in contig CP000903_GR.
KEGG	bwe:BcerKBAB4_3963.
PATRIC	19012573. VBIBacWei55973_4603.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000001971.
HOGENOM	HBG497643.
OMA	CNINVEK.
ProtClustDB	PRK00942.
Enzyme and pathway databases
BioCyc	BWEI315730:BCERKBAB4_3963-MONOMER.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGB_BACWK

Accession

Primary (citable) accession number: A9VG70

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program