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Protein

Anti-sigma F factor

Gene

spoIIAB

Organism
Bacillus weihenstephanensis (strain KBAB4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processSporulation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factorUniRule annotation (EC:2.7.11.1UniRule annotation)
Alternative name(s):
Stage II sporulation protein ABUniRule annotation
Gene namesi
Name:spoIIABUniRule annotation
Ordered Locus Names:BcerKBAB4_3904
OrganismiBacillus weihenstephanensis (strain KBAB4)
Taxonomic identifieri315730 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001308061 – 146Anti-sigma F factorAdd BLAST146

Interactioni

Protein-protein interaction databases

STRINGi315730.BcerKBAB4_3904

Structurei

3D structure databases

ProteinModelPortaliA9VFH8
SMRiA9VFH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anti-sigma-factor family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2172 LUCA
HOGENOMiHOG000269931
KOiK06379
OMAiHAYEDKI

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di3.30.565.10, 1 hit
HAMAPiMF_00637 Anti_sigma_F, 1 hit
InterProiView protein in InterPro
IPR010194 Anti-sigma_F
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
PANTHERiPTHR35526:SF2 PTHR35526:SF2, 1 hit
PfamiView protein in Pfam
PF13581 HATPase_c_2, 1 hit
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF55874 SSF55874, 1 hit
TIGRFAMsiTIGR01925 spIIAB, 1 hit

Sequencei

Sequence statusi: Complete.

A9VFH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNEMNLQFS ALSQNESFAR VTVAAFIAQL DPTMEELTEI KTVVSEAVTN
60 70 80 90 100
AIIHGYEGNA EGVVYISVIL EEAMVKLTIR DEGIGIFNLD EARQPLFTTK
110 120 130 140
PELERSGMGF TIMENFMDEV EVISNESFGT TIHLTKYLSN SNALCN
Length:146
Mass (Da):16,246
Last modified:February 5, 2008 - v1
Checksum:i0A2A23B73908D55C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000903 Genomic DNA Translation: ABY45072.1
RefSeqiWP_001243400.1, NC_010184.1

Genome annotation databases

EnsemblBacteriaiABY45072; ABY45072; BcerKBAB4_3904
GeneIDi29399720
KEGGibwe:BcerKBAB4_3904

Similar proteinsi

Entry informationi

Entry nameiSP2AB_BACWK
AccessioniPrimary (citable) accession number: A9VFH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 5, 2008
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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