ID   A9VAL2_MONBE            Unreviewed;       478 AA.
AC   A9VAL2;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   24-JAN-2024, entry version 64.
DE   RecName: Full=SH3 domain-containing YSC84-like protein 1 {ECO:0000256|ARBA:ARBA00019109};
GN   ORFNames=MONBRDRAFT_34268 {ECO:0000313|EMBL:EDQ85341.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ85341.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ85341.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- SIMILARITY: Belongs to the SH3YL1 family.
CC       {ECO:0000256|ARBA:ARBA00007761}.
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DR   EMBL; CH991574; EDQ85341.1; -; Genomic_DNA.
DR   RefSeq; XP_001749752.1; XM_001749700.1.
DR   AlphaFoldDB; A9VAL2; -.
DR   STRING; 81824.A9VAL2; -.
DR   EnsemblProtists; EDQ85341; EDQ85341; MONBRDRAFT_34268.
DR   GeneID; 5895050; -.
DR   KEGG; mbr:MONBRDRAFT_34268; -.
DR   eggNOG; KOG1843; Eukaryota.
DR   InParanoid; A9VAL2; -.
DR   OMA; NDAMYND; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0032587; C:ruffle membrane; IBA:GO_Central.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR   GO; GO:1900027; P:regulation of ruffle assembly; IBA:GO_Central.
DR   CDD; cd11841; SH3_SH3YL1_like; 1.
DR   CDD; cd11525; SYLF_SH3YL1_like; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR035511; SH3YL1_SH3.
DR   InterPro; IPR033643; SYLF_SH3YL1-like.
DR   InterPro; IPR007461; Ysc84_actin-binding.
DR   PANTHER; PTHR15629:SF2; SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1; 1.
DR   PANTHER; PTHR15629; SH3YL1 PROTEIN; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   Pfam; PF04366; Ysc84; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          416..477
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          262..337
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          355..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        262..290
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        361..395
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   478 AA;  50731 MW;  7E26E52A8A18866C CRC64;
     MAAVVARPHP RSAECRRAAT ILNEFTIPSA NRGPDKLIPQ GILAAAKGLA IITVFRIGFV
     VTVRAGSGLV VARDGSGNWS APTCIGMGGM GGGLEIGGEI TNFVIVLNSD RAVRAFSQRG
     QVTLGGSLSV AAGPLGRAAE ADVALNKPAA FYTYSRTRGL YAGLTIEGAV IMERRGANRK
     VYGTDVRSAD LLNGRVGRPR EAIPLYATCV HTTSLLAQLP KHEHSQYSAL EAATGGRLGS
     VVHGVDNALR NGTSAADTMS RLKSVAHRPT ASSSNSSSTK EASTARHSRS FSFRSKNKDS
     DGSTHAQRKS FFSRGSHHTS KSKHRDQADV SSNSTGGNML FEQDVKLSVR PVRGAPVRAT
     SAKSASAQAS KPARRSTKSN NSAGSASAAA SSTASTMADL PFTRHSSMAR EPDIWDDDVE
     VTALFDYQGT MDCDLSFRQG DRIKIITRTD SRHDWWEGEH DGRIGIFPAN FTSDIGKQ
//