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Protein

Histone-lysine N-methyltransferase

Gene

26549

Organism
Monosiga brevicollis (Choanoflagellate)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. methyltransferase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
ORF Names:26549Imported, 30554Imported
OrganismiMonosiga brevicollis (Choanoflagellate)Imported
Taxonomic identifieri81824 [NCBI]
Taxonomic lineageiEukaryotaChoanoflagellidaCodonosigidaeMonosiga
ProteomesiUP000001357 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi81824.JGI30554.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG2940.
InParanoidiA9V2P5.
KOiK11433.
OMAiSCHECIS.

Family and domain databases

InterProiIPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9V2P5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQVVRGSEA GKGDDGNAVT QPMPTPAPYT SVDEVMLPAR LQGRNNVYSG
60 70 80 90 100
CSCTGPCAPE TCSCLCNGRA RYYECNDNCA CDVATCRAGR TTQQPTALDI
110 120 130 140 150
RLVWTSERGH GLLTGTRIPV GTYVGHYTGQ LVNVATARAR DSAADAVSPV
160 170 180 190 200
HTYLLVLREH TQRGVLTTAV DAKEYGNLTR FINHSCAPNL ELRPVRLGFV
210 220 230 240 250
PRLAFFALTD IPAETELTFD YGGAPPSAKI ATTLPADTDT GAPRHKRHVT
260 270
APELALSAKP CRCGAPTCRG FLPLTIW
Length:277
Mass (Da):29,707
Last modified:February 5, 2008 - v1
Checksum:i5A1F4A3FB3EEE20C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH991605 Genomic DNA. Translation: EDQ84136.1.
CH991555 Genomic DNA. Translation: EDQ88409.1.
RefSeqiXP_001747002.1. XM_001746950.1.
XP_001751054.1. XM_001751002.1.

Genome annotation databases

GeneIDi5892072.
5896315.
KEGGimbr:MONBRDRAFT_26549.
mbr:MONBRDRAFT_30554.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH991605 Genomic DNA. Translation: EDQ84136.1.
CH991555 Genomic DNA. Translation: EDQ88409.1.
RefSeqiXP_001747002.1. XM_001746950.1.
XP_001751054.1. XM_001751002.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi81824.JGI30554.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5892072.
5896315.
KEGGimbr:MONBRDRAFT_26549.
mbr:MONBRDRAFT_30554.

Phylogenomic databases

eggNOGiCOG2940.
InParanoidiA9V2P5.
KOiK11433.
OMAiSCHECIS.

Family and domain databases

InterProiIPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MX1 / ATCC 50154Imported.

Entry informationi

Entry nameiA9V2P5_MONBE
AccessioniPrimary (citable) accession number: A9V2P5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: April 29, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.