A9UR24 (A9UR24_MONBE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyruvate kinase RuleBase RU000504
EC=2.7.1.40 RuleBase RU000504

Gene names

ORF Names:

14293

Organism

Monosiga brevicollis (Choanoflagellate) [Reference proteome]

Taxonomic identifier

81824 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Choanoflagellida › Codonosigidae › Monosiga

Protein attributes

Sequence length	517 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + pyruvate = ADP + phosphoenolpyruvate. RuleBase RU000504
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5. RuleBase RU000504
Sequence similarities	Belongs to the pyruvate kinase family. RuleBase RU000504

Ontologies

Keywords
Biological process	Glycolysis RuleBase RU000504
Ligand	Magnesium RuleBase RU000504
Molecular function	Kinase RuleBase RU000504 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: InterPro potassium ion binding Inferred from electronic annotation. Source: InterPro pyruvate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9UR24 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: CC33AAA35A2F2DE8	FASTA	517	55,720
	10 20 30 40 50 60 MARPSQQEAQ AAMTGLQMRS SLNIYSDPAH ARKTGIICTI GPASRSVELL TSLMKAGMNI 70 80 90 100 110 120 VRLNFSHGTH EYHAGTIANA REAANAHNRP IAIALDTKGP EIRTGLLEGF NENPRLELEL 130 140 150 160 170 180 GQGSQITVTT DDAFAEKCTA DVLYVDYKNI TKVMKPGNLI YVDDGLISLQ VDSISSDSMK 190 200 210 220 230 240 CTVVNSGKLG SKKGVNLPNV KVDLPAISEK DKSDLTFGVE QGVDMIFASF IRKASDVQAI 250 260 270 280 290 300 REHLGEAGKN IKIICKIENH EGVQNFDEIL SVVDGVMVAR GDLGIEIPAE KVFLAQKMMI 310 320 330 340 350 360 AKCNLAGKPV ICATQMLESM IKAPRPTRAE GSDVANAVLD GADCVMLSGE TAKGDYPVEA 370 380 390 400 410 420 VKMMASIAVE AEAAVNLRDL REEMRMLTPK PTKTTETCAT AAVDASISSQ AAAIICLTIS 430 440 450 460 470 480 GRTARLISKW KPICPVVAVT RQHSVARQMH LHFGVSPMCY DTSKKDTWAG DVDKRFSWAM 490 500 510 ENGKALKLFK SGDVVVGVHG WQTGPGHTNT IRMLVVP

References

[1]

"The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans." JGI Sequencing King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J., Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D., Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M. , Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S., Richter D.J., Salamov A., Sequencing J.G., Bork P., Lim W.A., Manning G., Miller W.T., McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D. Nature 451:783-788(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MX1 / ATCC 50154.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH991544 Genomic DNA. Translation: EDQ92173.1.
RefSeq	XP_001743459.1. XM_001743407.1.
3D structure databases
ProteinModelPortal	A9UR24.
SMR	A9UR24. Positions 7-517.
ModBase	Search...
Protein-protein interaction databases
STRING	81824.JGI14293.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5888553.
KEGG	mbr:MONBRDRAFT_14293.
Phylogenomic databases
eggNOG	COG0469.
KO	K00873.
OMA	VKMMATI.
Enzyme and pathway databases
UniPathway	UPA00109; UER00188.
Family and domain databases
Gene3D	2.40.33.10. 1 hit. 3.20.20.60. 2 hits. 3.40.1380.20. 1 hit.
InterPro	IPR001697. Pyr_Knase. IPR015813. Pyrv/PenolPyrv_Kinase. IPR011037. Pyrv_Knase-like_insert_dom. IPR015794. Pyrv_Knase_a/b. IPR018209. Pyrv_Knase_AS. IPR015793. Pyrv_Knase_brl. IPR015795. Pyrv_Knase_C. IPR015806. Pyrv_Knase_insert_dom. [Graphical view]
PANTHER	PTHR11817. PTHR11817. 1 hit.
Pfam	PF00224. PK. 1 hit. PF02887. PK_C. 1 hit. [Graphical view]
PRINTS	PR01050. PYRUVTKNASE.
SUPFAM	SSF50800. PK_B_barrel_like. 1 hit. SSF52935. Pyruvate_kinase. 1 hit. SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
TIGRFAMs	TIGR01064. pyruv_kin. 1 hit.
PROSITE	PS00110. PYRUVATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9UR24_MONBE

Accession

Primary (citable) accession number: A9UR24

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	April 3, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)