A9UQS1 (EIF3E_MONBE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Eukaryotic translation initiation factor 3 subunit E
Short name=eIF3e

Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 6

Gene names

ORF Names:

13685

Organism

Monosiga brevicollis (Choanoflagellate) [Reference proteome]

Taxonomic identifier

81824 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Choanoflagellida › Codonosigidae › Monosiga

Protein attributes

Sequence length	485 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03004
Subunit structure	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the eIF-3 subunit E family. Contains 1 PCI domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 485	485	Eukaryotic translation initiation factor 3 subunit E HAMAP-Rule MF_03004		PRO_0000365994
Regions
	Domain	284 – 388	105	PCI

Sequences

	Sequence		Length	Mass (Da)
	A9UQS1 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 6E1576B6E0D02C5D	FASTA	485	55,760
	10 20 30 40 50 60 MAAHDLTQAI CQNLDPHLIL PLLDHCVDLD IYNEADLKRA KMQVLSRTRL IEQALELADA 70 80 90 100 110 120 TEKKDLDARM RSISEEEKTW EKQLEPVFEM FENDEVLSII EATKNKDSLL SELEPYGFTE 130 140 150 160 170 180 NTADLLYHGS KFYFDRGQYD LAHGLLYNYR AVSTDDKLKF TALWGKLAAA ILSGNWQTAQ 190 200 210 220 230 240 EDMYLLLEYI DGGKNELTAV EQLQQRNWLL HWSLFVFFNQ PDGPDGIVDL FMNKETCTNA 250 260 270 280 290 300 MQTIAPHLFR YATAVAIMSR RKKRDVMWEF VGIARQDKDL GDDPVVGFLV SLIKDFDFVT 310 320 330 340 350 360 AEEKLQQCRE VLSKDYFLAE MTDEFINTAQ LYLFEVYLRV HSRVSIKNAA TRLGKSEDDA 370 380 390 400 410 420 EEWLVKLIRD AKLDAQIDPA SGEIHITKPV TTVYQHVLDR TKNLQYRTYV IVESLHHLHP 430 440 450 460 470 480 NGAFHHSNSS IPALFRRMMN EQLQGGGKSN KKGDYKKGDY KKGGDFKKGG DFKKGGDHKK RAWVK

References

[1]

"The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans." JGI Sequencing King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J., Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D., Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M. , Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S., Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T., McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D. Nature 451:783-788(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MX1 / ATCC 50154.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH991543 Genomic DNA. Translation: EDQ93095.1.
RefSeq	XP_001742857.1. XM_001742805.1.
3D structure databases
ProteinModelPortal	A9UQS1.
ModBase	Search...
Protein-protein interaction databases
STRING	81824.JGI13685.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5887340.
KEGG	mbr:MONBRDRAFT_13685.
Phylogenomic databases
eggNOG	NOG324642.
KO	K03250.
OMA	HNASEED.
ProtClustDB	CLSZ2429318.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
HAMAP	MF_03004. eIF3e.
InterPro	IPR019010. eIF3_su6_N. IPR000717. PCI_dom. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF09440. eIF3_N. 1 hit. PF01399. PCI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EIF3E_MONBE

Accession

Primary (citable) accession number: A9UQS1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)