A9UK92 (A9UK92_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
RCG44348, isoform CRA_a EMBL EDL87505.1

Submitted name:
SIAH EMBL AAV87215.1

Gene names

Name:	Siah1a RGD 620449
ORF Names:	rCG_44348 EMBL EDL87505.1

Organism

Rattus norvegicus (Rat) EMBL AAV87215.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 RING-type zinc finger. SAAS SAAS013323

Ontologies

Keywords
Domain	Zinc-finger SAAS SAAS013323 RuleBase RU000353
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Biological process	multicellular organismal development Inferred from electronic annotation. Source: InterPro ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	ubiquitin-protein ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9UK92 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 852EADC5DD4A4FFA	FASTA	282	31,137
	10 20 30 40 50 60 MSRQTATALP TGTSKCPPSQ RVPALTGTTA SNNDLASLFE CPVCFDYVLP PILQCQSGHL 70 80 90 100 110 120 VCSNCRPKLT CCPTCRGPLG SIRNLAMEKV ANSVLFPCKY ASSGCEITLP HTEKAEHEEL 130 140 150 160 170 180 CEFRPYSCPC PGASCKWQGS LDAVMPHLMH QHKSITTLQG EDIVFLATDI NLPGAVDWVM 190 200 210 220 230 240 MQSCFGFHFM LVLEKQEKYD GHQQFFAIVQ LIGTRKQAEN FAYRLELNGH RRRLTWEATP 250 260 270 280 RSIHEGIATA IMNSDCLVFD TSIAQLFAEN GNLGINVTIS MC

References

[1]	"Gene and alternative splicing annotation with AIR." Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G. Genome Res. 15:54-66(2005) [PubMed: 15632090] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDL87505.1.
[2]	"Glyceraldeyde-3-Phosphate Dehydrogenase (GAPDH) in Cell Death: Binding and Stabilization of Siah in the Nucleus." Sawa A., Park J., Agrawal N., Hanle L.J., Luo X., Takahashi M., Snyder S.H. Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDL87505.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY681965 mRNA. Translation: AAV87215.1. CH474037 Genomic DNA. Translation: EDL87505.1. CH474037 Genomic DNA. Translation: EDL87506.1.
IPI	IPI00200708.
RefSeq	NP_543181.2. NM_080905.2.
UniGene	Rn.73937.
3D structure databases
ProteinModelPortal	A9UK92.
SMR	A9UK92. Positions 33-282.
ModBase	Search...
Protein-protein interaction databases
STRING	A9UK92.
Proteomic databases
PRIDE	A9UK92.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	140941.
KEGG	rno:140941.
Organism-specific databases
CTD	20437.
RGD	620449. Siah1a.
Phylogenomic databases
HOVERGEN	HBG055701.
OMA	PLGNIRN.
PhylomeDB	A9UK92.
Gene expression databases
Genevestigator	A9UK92.
Family and domain databases
InterPro	IPR004162. 7-in-absentia-prot. IPR018121. 7-in-absentia-prot_TRAF-dom. IPR013323. SIAH-type. IPR008974. TRAF-like. IPR013322. TRAF-type. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR013010. Znf_SIAH. [Graphical view]
Gene3D	G3DSA:3.90.890.10. SIAH-type. 1 hit. G3DSA:2.60.210.10. TRAF-type. 1 hit. G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 1 hit.
KO	K04506.
PANTHER	PTHR10315. Sina. 1 hit.
Pfam	PF03145. Sina. 1 hit. [Graphical view]
SMART	SM00184. RING. 1 hit. [Graphical view]
SUPFAM	SSF49599. Traf_like. 1 hit.
PROSITE	PS50089. ZF_RING_2. 1 hit. PS51081. ZF_SIAH. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	620838.

Entry information

Entry name

A9UK92_RAT

Accession

Primary (citable) accession number: A9UK92

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	November 16, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)