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Protein
Submitted name:

Low affinity neurotrophin p75 receptor

Gene

NGFR

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Low affinity neurotrophin p75 receptorImported
Gene namesi
Name:NGFRImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei239 – 259HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500274459820 – 414Sequence analysisAdd BLAST395

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi76 ↔ 89PROSITE-ProRule annotation
Disulfide bondi79 ↔ 97PROSITE-ProRule annotation
Disulfide bondi115 ↔ 128PROSITE-ProRule annotation
Disulfide bondi118 ↔ 136PROSITE-ProRule annotation
Disulfide bondi139 ↔ 154PROSITE-ProRule annotation
Disulfide bondi157 ↔ 170PROSITE-ProRule annotation
Disulfide bondi160 ↔ 178PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PaxDbiA9UGK7.

Structurei

3D structure databases

ProteinModelPortaliA9UGK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 97TNFR-CysInterPro annotationAdd BLAST42
Repeati56 – 97TNFR-CysPROSITE-ProRule annotationAdd BLAST42
Domaini98 – 136TNFR-CysInterPro annotationAdd BLAST39
Repeati98 – 136TNFR-CysPROSITE-ProRule annotationAdd BLAST39
Domaini138 – 178TNFR-CysInterPro annotationAdd BLAST41
Repeati138 – 178TNFR-CysPROSITE-ProRule annotationAdd BLAST41
Domaini331 – 408DeathInterPro annotationAdd BLAST78

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IQFC. Eukaryota.
ENOG4111F3C. LUCA.
HOVERGENiHBG060431.
KOiK02583.

Family and domain databases

CDDicd13416. TNFRSF16. 1 hit.
InterProiView protein in InterPro
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022325. TNFR_16.
IPR034046. TNFRSF16_N.
PfamiView protein in Pfam
PF00531. Death. 1 hit.
PF00020. TNFR_c6. 2 hits.
PRINTSiPR01966. TNFACTORR16.
SMARTiView protein in SMART
SM00005. DEATH. 1 hit.
SM00208. TNFR. 4 hits.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50017. DEATH_DOMAIN. 1 hit.
PS00652. TNFR_NGFR_1. 2 hits.
PS50050. TNFR_NGFR_2. 3 hits.

Sequencei

Sequence statusi: Complete.

A9UGK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGFVPLLLL LLPAGPTWGS KCLTKMYTTS GECCKACNLG EGVVQPCGVN
60 70 80 90 100
QTVCEPCLDS VTYSDTVSAT EPCKPCTQCV GLHSMSAPCV ESDDAVCRCA
110 120 130 140 150
YGYFQDELSG SCKECSICEV GFGLMFPCRD SQDTVCEECP EGTFSDEANF
160 170 180 190 200
VDPCLPCTIC EENEVMVKEC TATSDAECRD LHPRWTTHTP SLAGSDSPEP
210 220 230 240 250
ITRDPFNTEG MATTLADIVT TVMGSSQPVV SRGTADNLIP VYCSILAAVV
260 270 280 290 300
VGLVAYIAFK RWNSCKQNKQ GANNRPVNQT PSPEGEKLHS DSGISVDSQS
310 320 330 340 350
LHDQQPPNQS TQGPAPKGDG SLYASLPPSK QEEVEKLLSS SAEETWRQLA
360 370 380 390 400
GELGYKEDLI DCFTREESPA RALLADWSAK ETATLDALLV ALRKIQRGDI
410
AESLYSESTA TSPV
Length:414
Mass (Da):44,397
Last modified:February 5, 2008 - v1
Checksum:i9756A14396F43673
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU282004 mRNA. Translation: ABX79794.1.
RefSeqiNP_001139605.1. NM_001146133.1.
UniGeneiGga.39799.

Genome annotation databases

GeneIDi425805.
KEGGigga:425805.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA9UGK7_CHICK
AccessioniPrimary (citable) accession number: A9UGK7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: July 5, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation