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Protein

Hexokinase

Gene

hxk3

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:hxk3Imported
ORF Names:PHYPADRAFT_228858Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)Imported
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella
ProteomesiUP000006727: Partially assembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi3218.JGI227173.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 2 hexokinase type-2 domains.UniRule annotation

Phylogenomic databases

InParanoidiA9U0F4.
KOiK00844.
OMAiPVTEYDE.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9U0F4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQSKVLVGV YIACAAAACA TAAVAVTQRL KVRAQKCTAR KILVEFQEAC
60 70 80 90 100
ETPLPRLRQV VDAMAVEMHA GLVSEGGSKL KMLPTFIDRL PNGSEKGLYY
110 120 130 140 150
AVDLGGTNFR VLRVQLGGLE GRVIKQEYEE VAIPPELMLG TSEQLFHFIA
160 170 180 190 200
KELAGFVARE GEEFRLGDGQ SREIGFTFSF PCKQTAVNSG TLLQWTKGFK
210 220 230 240 250
VNDAIGQDVV AALQKCIERL GCKMRIAALV NDTVGTLAGG RYWNNDVMIA
260 270 280 290 300
VILGTGTNAC YVERAESISK WTGELPKSGQ MVINMEWGNF WSSHLPRTYV
310 320 330 340 350
DELLDSESLH PGEYGFEKMI SGMYLGDCVR RVLVRMAQEA GIFGPHVPHT
360 370 380 390 400
LLESFSLQTP EMSRMHHDDS SDLKVVAEVL KRLYGIQNTT VGIRKIVVAV
410 420 430 440 450
CDTTCQRGAR LAAAGIVGIL KKIGRDGSTA NGLMRRNDTN GIHDELSVNS
460 470 480 490 500
TPGSGKTVVA MDGGLYEHYS KFRNYMQEAV RELLGDASKN VSIELSKDGS
510
GIGAALLAAS YAEYVPS
Length:517
Mass (Da):56,217
Last modified:February 5, 2008 - v1
Checksum:iD0A949429BCFD81F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS545286 Genomic DNA. Translation: EDQ50852.1.
RefSeqiXP_001784334.1. XM_001784282.1.
UniGeneiPpa.4843.

Genome annotation databases

GeneIDi5947550.
KEGGippp:PHYPADRAFT_228858.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS545286 Genomic DNA. Translation: EDQ50852.1.
RefSeqiXP_001784334.1. XM_001784282.1.
UniGeneiPpa.4843.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3218.JGI227173.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5947550.
KEGGippp:PHYPADRAFT_228858.

Phylogenomic databases

InParanoidiA9U0F4.
KOiK00844.
OMAiPVTEYDE.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants."
    Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H., Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T., Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A., Suzuki Y.
    , Hashimoto S.-I., Yamaguchi K., Sugano A., Kohara Y., Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E., Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M., Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J., Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B., Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A., Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y., Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M., Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S., Boore J.L.
    Science 319:64-69(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Gransden 2004Imported.

Entry informationi

Entry nameiA9U0F4_PHYPA
AccessioniPrimary (citable) accession number: A9U0F4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: March 4, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.