ID   A9TW25_PHYPA            Unreviewed;       961 AA.
AC   A9TW25;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   RecName: Full=phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00012305};
DE            EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305};
GN   ORFNames=PHYPA_020563 {ECO:0000313|EMBL:PNR37454.1};
OS   Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC   Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX   NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR37454.1};
RN   [1] {ECO:0000313|EMBL:PNR37454.1, ECO:0000313|Proteomes:UP000006727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c16_6580V3.1,
RC   ECO:0000313|Proteomes:UP000006727};
RX   PubMed=18079367; DOI=10.1126/science.1150646;
RA   Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA   Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA   Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA   Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA   Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA   Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA   Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA   Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA   Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA   Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA   Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA   Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA   Boore J.L.;
RT   "The Physcomitrella genome reveals evolutionary insights into the conquest
RT   of land by plants.";
RL   Science 319:64-69(2008).
RN   [2] {ECO:0000313|EMBL:PNR37454.1, ECO:0000313|Proteomes:UP000006727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c16_6580V3.1,
RC   ECO:0000313|Proteomes:UP000006727};
RX   PubMed=29237241; DOI=10.1111/tpj.13801;
RA   Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA   Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA   Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA   Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA   Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA   Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA   Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA   Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA   Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA   Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA   Schmutz J., Rensing S.A.;
RT   "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT   structure and evolution.";
RL   Plant J. 93:515-533(2018).
RN   [3] {ECO:0000313|EnsemblPlants:Pp3c16_6580V3.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (DEC-2020) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008346}.
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DR   EMBL; ABEU02000016; PNR37454.1; -; Genomic_DNA.
DR   RefSeq; XP_001782799.1; XM_001782747.1.
DR   AlphaFoldDB; A9TW25; -.
DR   SMR; A9TW25; -.
DR   STRING; 3218.A9TW25; -.
DR   PaxDb; 3218-PP1S341_58V6-1; -.
DR   EnsemblPlants; Pp3c16_6580V3.1; Pp3c16_6580V3.1; Pp3c16_6580.
DR   EnsemblPlants; Pp3c16_6580V3.2; Pp3c16_6580V3.2; Pp3c16_6580.
DR   EnsemblPlants; Pp3c16_6580V3.3; Pp3c16_6580V3.3; Pp3c16_6580.
DR   EnsemblPlants; Pp3c16_6580V3.4; Pp3c16_6580V3.4; Pp3c16_6580.
DR   Gramene; Pp3c16_6580V3.1; Pp3c16_6580V3.1; Pp3c16_6580.
DR   Gramene; Pp3c16_6580V3.2; Pp3c16_6580V3.2; Pp3c16_6580.
DR   Gramene; Pp3c16_6580V3.3; Pp3c16_6580V3.3; Pp3c16_6580.
DR   Gramene; Pp3c16_6580V3.4; Pp3c16_6580V3.4; Pp3c16_6580.
DR   eggNOG; ENOG502QPVS; Eukaryota.
DR   HOGENOM; CLU_006557_2_0_1; -.
DR   InParanoid; A9TW25; -.
DR   OMA; WAFGEQL; -.
DR   OrthoDB; 355614at2759; -.
DR   Proteomes; UP000006727; Chromosome 16.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IBA:GO_Central.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF33; PHOSPHOENOLPYRUVATE CARBOXYLASE 3; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006727}.
FT   ACT_SITE        171
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        599
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10112"
SQ   SEQUENCE   961 AA;  109248 MW;  8E6A41D2C252E28E CRC64;
     MAYLQKIASI DAQMRLLVPK RVSDDDKLIE YDALLLDRFL DILQDLHGKE IKEAVQNCYE
     LSGAFCKTDG KDEAKLQQLS SLLNNLDAGD SIVVASSFSH MLNLGNLAEE VQIAYRRPGS
     RKGDLGDESS ALTESDLDQT FQRLVKQLKK TPEEIFEALK DQTVDLVLTA HPTQSVRRSL
     LQKHSRIRDC LSQMYGKDIT AEEKQELDEA LQREIQAAFR TDEIRRSQPT PQDEMRAGMS
     YFHETIWNGL PKFLRRVDTA LKTIGVKERL PHNVPLIQFS SWMGGDRDGN PRVTPDVTRD
     VCLLARLMAA NLYFAQIEDL MFELSMWRCS DELKQRVATL EAHAKKEAKH YIEFWKHIPP
     NEPFRVLLGD MRDKLYNTRE RMRQLLASGK SDINIEDTFT DASQILEPLE LCHRSLCETG
     DKPIADGSLL DFMRQVSCFG LSLVKLDIRQ ESERHTDVLD TITNYLGIGS YRDWSEEQRQ
     EWLLSELRGK RPLFGDDLPT TEEVQDVLDT FRVIAELPTD SFGAYIISMA TSPSDVLAVE
     LLQRECRVPK PLRVVPLFEK LADLESAPAA LSRLFSIDWY LNHIKGKQEV MIGYSDSGKD
     AGRLSAAWAM YKAQEDLVKV AKQYGIRLTM FHGRGGTVGR GGGPTHLAIL SQPPDTINGS
     LRVTIQGEVI EQSFGEEHLC FRTLQRFTAA TLEHGMHPPI APKPEWRNLM DSMAVTATEE
     YRSIVFQNPR FVEYFRTATP ELEYGRMNIG SRPSKRKPSG GIESLRAIPW IFAWTQTRFH
     LPVWLGLGAA LRQALEAEPN NMTVLSRMYD QWPFFRVTID LVEMVFAKGD PRIAELYDSL
     LVSEELRPLG DELREKYEET KAHLLKIARH KDILQGNPTL KQRLRLREPY ITALNIQQAF
     TLKKMRDRSA YYATLQPESP RPTKAAAELV TLNPTTEFAP GLEDTLILTM KGIAAGIQNT
     G
//