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Protein

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Gene

PHYPA_030942

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).UniRule annotation

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes fumarate from succinate (eukaryal route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (PHYPA_030942), Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (PHYPADRAFT_181904), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (PHYPADRAFT_5986), Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (PHYPA_009438), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (PHYPA_016135)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes fumarate from succinate (eukaryal route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transportUniRule annotation, Transport, Tricarboxylic acid cycleUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01006

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialUniRule annotation (EC:1.3.5.1UniRule annotation)
Gene namesi
ORF Names:PHYPA_030942Imported, PHYPADRAFT_196863Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella
Proteomesi
  • UP000006727 Componenti: Chromosome 27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiA9TP02

Interactioni

Protein-protein interaction databases

STRINGi3218.PP1S276_97V6.1

Structurei

3D structure databases

ProteinModelPortaliA9TP02
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 444FAD_binding_2InterPro annotationAdd BLAST397
Domaini499 – 631Succ_DH_flav_CInterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

eggNOGiKOG2403 Eukaryota
COG1053 LUCA
InParanoidiA9TP02
KOiK00234
OMAiGDSPWEH

Family and domain databases

Gene3Di3.50.50.60, 2 hits
3.90.700.10, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR003952 FRD_SDH_FAD_BS
IPR037099 Fum_R/Succ_DH_flav-like_C_sf
IPR015939 Fum_Rdtase/Succ_DH_flav-like_C
IPR027477 Succ_DH/fumarate_Rdtase_cat_sf
IPR011281 Succ_DH_flav_su_fwd
IPR014006 Succ_Dhase_FrdA_Gneg
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PF02910 Succ_DH_flav_C, 1 hit
SUPFAMiSSF46977 SSF46977, 1 hit
SSF51905 SSF51905, 2 hits
SSF56425 SSF56425, 1 hit
TIGRFAMsiTIGR01816 sdhA_forward, 1 hit
TIGR01812 sdhA_frdA_Gneg, 1 hit
PROSITEiView protein in PROSITE
PS00504 FRD_SDH_FAD_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

A9TP02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRRVVESST KRLLRQRNGA LARSRSQQPK RGFAVDAKSY PIVDHTYDAI
60 70 80 90 100
VVGAGGAGLR AAIGLSETGF TTACITKLFP TRSHTVAAQG GINAALGNMT
110 120 130 140 150
EDDWRWHMYD TVKGSDWLGD QDAIQYMCRE APKAVIELEN YGLPFSRTED
160 170 180 190 200
GKIYQRAFGG QSLNFGKGGQ AYRCAAAADR TGHAMLHTLY GQAMKHNTQF
210 220 230 240 250
FVEYFALDLI MDEQGACRGV IALNMEDGTL HRFRAMNTIL ATGGYGRAYF
260 270 280 290 300
SATSAHTCTG DGNAMAARAG IPLQDLEFVQ FHPTGIYGAG CLITEGSRGE
310 320 330 340 350
GGILRNSEGE RFMERYAPTA KDLASRDVVS RSMTMEIREG RGVGPEKDHI
360 370 380 390 400
YLHLNHLPPE VLKERLPGIS ETAAIFAGVD VTKEPIPVLP TVHYNMGGIP
410 420 430 440 450
TNYHGEVLTK KGDDPDCMIP GLMAAGEAAC ASVHGANRLG ANSLLDIVIF
460 470 480 490 500
GRACANRVAE MFKPGQKQPE LPKDAGEKTI AWLDKLRYAN GDIPTANIRN
510 520 530 540 550
KMQRVMQNNA AVFRTQETLE EGCKLIDETV DSLSRVKTND RSLTWNTDLI
560 570 580 590 600
ETIELENLLI NASVTMHSAE ARKESRGAHA REDFTTRDDE KWMKHTLGYW
610 620 630
ENDRVRLDYR PVHMNTLDDE VETFPPKARV Y
Length:631
Mass (Da):69,687
Last modified:February 5, 2008 - v1
Checksum:iDDAEF954B32867BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS545165 Genomic DNA Translation: EDQ54899.1
ABEU02000027 Genomic DNA Translation: PNR26367.1
RefSeqiXP_001780340.1, XM_001780288.1
UniGeneiPpa.7495

Genome annotation databases

EnsemblPlantsiPP1S276_97V6.1; PP1S276_97V6.1; PP1S276_97V6
PP1S276_97V6.2; PP1S276_97V6.2; PP1S276_97V6
PP1S276_97V6.3; PP1S276_97V6.3; PP1S276_97V6
PP1S276_97V6.4; PP1S276_97V6.4; PP1S276_97V6
PP1S276_97V6.5; PP1S276_97V6.5; PP1S276_97V6
GeneIDi5943517
GrameneiPP1S276_97V6.1; PP1S276_97V6.1; PP1S276_97V6
PP1S276_97V6.2; PP1S276_97V6.2; PP1S276_97V6
PP1S276_97V6.3; PP1S276_97V6.3; PP1S276_97V6
PP1S276_97V6.4; PP1S276_97V6.4; PP1S276_97V6
PP1S276_97V6.5; PP1S276_97V6.5; PP1S276_97V6
KEGGippp:PHYPADRAFT_196863

Similar proteinsi

Entry informationi

Entry nameiA9TP02_PHYPA
AccessioniPrimary (citable) accession number: A9TP02
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: April 25, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health