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Protein

Inositol-1-monophosphatase

Gene

PHYPADRAFT_223991

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Myo-inositol phosphate + H2O = myo-inositol + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: myo-inositol biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Inositol-1-monophosphatase (PHYPADRAFT_173465), Inositol-1-monophosphatase (PHYPADRAFT_205419), Inositol-1-monophosphatase (PHYPADRAFT_223991), Inositol-1-monophosphatase (PHYPADRAFT_224574)
This subpathway is part of the pathway myo-inositol biosynthesis, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate, the pathway myo-inositol biosynthesis and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00823; UER00788.

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol-1-monophosphataseUniRule annotation (EC:3.1.3.25UniRule annotation)
Gene namesi
ORF Names:PHYPADRAFT_223991Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)Imported
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella
Proteomesi
  • UP000006727 Componenti: Partially assembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi3218.PP1S275_35V6.2.

Structurei

3D structure databases

ProteinModelPortaliA9TNR4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inositol monophosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2951. Eukaryota.
COG0483. LUCA.
InParanoidiA9TNR4.
KOiK10047.
OMAiHAWDCLA.

Family and domain databases

CDDicd01639. IMPase. 1 hit.
InterProiView protein in InterPro
IPR033942. IMPase.
IPR020583. Inositol_monoP_metal-BS.
IPR020552. Inositol_monoPase_Li-sen.
IPR000760. Inositol_monophosphatase-like.
IPR020550. Inositol_monophosphatase_CS.
PANTHERiPTHR20854. PTHR20854. 1 hit.
PfamiView protein in Pfam
PF00459. Inositol_P. 1 hit.
PRINTSiPR00377. IMPHPHTASES.
PR00378. LIIMPHPHTASE.
PROSITEiView protein in PROSITE
PS00629. IMP_1. 1 hit.
PS00630. IMP_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A9TNR4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLQQCEDLE TCLAVAVDVA KKAGQIIKDG FHIAKAVEHK GMVDLVTETD
60 70 80 90 100
KACEDLIFTQ LKTSFPSHEL IGEEESSESG IPLLTDAPTW VVDPLDGTTN
110 120 130 140 150
FVHKFPFVCV SIGLVINKVS VVGVVYNPLL EELFTAIQGQ GAFLNGERIY
160 170 180 190 200
ASSQEHIGNG LLATEIGTKR DKHTVDRTTN LINDMLYKVR SLRLSGSCAM
210 220 230 240 250
NLVGVACGRL DMFYELGFGG PWDVAAGTLI LREAGGLVYD PSGGEFDMMS
260 270
HLIAASNGHL KQSLVDCLVD YL
Length:272
Mass (Da):29,409
Last modified:February 5, 2008 - v1
Checksum:i669C09D31F1383AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS545164 Genomic DNA. Translation: EDQ54908.1.
RefSeqiXP_001780244.1. XM_001780192.1.
UniGeneiPpa.7185.

Genome annotation databases

EnsemblPlantsiPP1S275_35V6.2; PP1S275_35V6.2; PP1S275_35V6.
PP1S275_35V6.4; PP1S275_35V6.4; PP1S275_35V6.
GeneIDi5943476.
GrameneiPP1S275_35V6.2; PP1S275_35V6.2; PP1S275_35V6.
PP1S275_35V6.4; PP1S275_35V6.4; PP1S275_35V6.
KEGGippp:PHYPADRAFT_223991.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA9TNR4_PHYPA
AccessioniPrimary (citable) accession number: A9TNR4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: July 5, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported