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Protein

Inositol-1-monophosphatase

Gene

PHYPA_026708

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Myo-inositol phosphate + H2O = myo-inositol + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: myo-inositol biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Inositol-1-monophosphatase (PHYPA_026708), Inositol-1-monophosphatase (PHYPA_025776), Inositol-1-monophosphatase (PHYPA_025886), Inositol-1-monophosphatase (PHYPA_023803), Inositol-1-monophosphatase (PHYPA_026342)
This subpathway is part of the pathway myo-inositol biosynthesis, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate, the pathway myo-inositol biosynthesis and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00823; UER00788

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol-1-monophosphataseUniRule annotation (EC:3.1.3.25UniRule annotation)
Gene namesi
ORF Names:PHYPA_026708Imported, PHYPADRAFT_223991Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella
Proteomesi
  • UP000006727 Componenti: Chromosome 22

Interactioni

Protein-protein interaction databases

STRINGi3218.PP1S275_35V6.2

Structurei

3D structure databases

ProteinModelPortaliA9TNR4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inositol monophosphatase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG2951 Eukaryota
COG0483 LUCA
InParanoidiA9TNR4
KOiK10047
OMAiVEWGNQR

Family and domain databases

CDDicd01639 IMPase, 1 hit
InterProiView protein in InterPro
IPR033942 IMPase
IPR020583 Inositol_monoP_metal-BS
IPR020552 Inositol_monoPase_Li-sen
IPR000760 Inositol_monophosphatase-like
IPR020550 Inositol_monophosphatase_CS
PfamiView protein in Pfam
PF00459 Inositol_P, 1 hit
PRINTSiPR00377 IMPHPHTASES
PR00378 LIIMPHPHTASE
PROSITEiView protein in PROSITE
PS00629 IMP_1, 1 hit
PS00630 IMP_2, 1 hit

Sequencei

Sequence statusi: Complete.

A9TNR4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLQQCEDLE TCLAVAVDVA KKAGQIIKDG FHIAKAVEHK GMVDLVTETD
60 70 80 90 100
KACEDLIFTQ LKTSFPSHEL IGEEESSESG IPLLTDAPTW VVDPLDGTTN
110 120 130 140 150
FVHKFPFVCV SIGLVINKVS VVGVVYNPLL EELFTAIQGQ GAFLNGERIY
160 170 180 190 200
ASSQEHIGNG LLATEIGTKR DKHTVDRTTN LINDMLYKVR SLRLSGSCAM
210 220 230 240 250
NLVGVACGRL DMFYELGFGG PWDVAAGTLI LREAGGLVYD PSGGEFDMMS
260 270
HLIAASNGHL KQSLVDCLVD YL
Length:272
Mass (Da):29,409
Last modified:February 5, 2008 - v1
Checksum:i669C09D31F1383AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS545164 Genomic DNA Translation: EDQ54908.1
ABEU02000022 Genomic DNA Translation: PNR30392.1
RefSeqiXP_001780244.1, XM_001780192.1
UniGeneiPpa.7185

Genome annotation databases

EnsemblPlantsiPP1S275_35V6.2; PP1S275_35V6.2; PP1S275_35V6
PP1S275_35V6.4; PP1S275_35V6.4; PP1S275_35V6
GeneIDi5943476
GrameneiPP1S275_35V6.2; PP1S275_35V6.2; PP1S275_35V6
PP1S275_35V6.4; PP1S275_35V6.4; PP1S275_35V6
KEGGippp:PHYPADRAFT_223991

Similar proteinsi

Entry informationi

Entry nameiA9TNR4_PHYPA
AccessioniPrimary (citable) accession number: A9TNR4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: April 25, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health