Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA ligase

Gene

PHYPADRAFT_221958

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PHYPADRAFT_221958Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi3218.PP1S223_54V6.1

Structurei

3D structure databases

ProteinModelPortaliA9TG22
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini388 – 525DNA_LIGASE_A3InterPro annotationAdd BLAST138

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili229 – 249Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiA9TG22
KOiK10747

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

A9TG22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEKKVVAST AAEAVVLLTK KETDFDPEAA AFWKPGQPVP FLFLASALDI
60 70 80 90 100
ISDESGRLAM TNILCNVFRT VIATTPKDLL AVVTLSANRI APAHEGVELG
110 120 130 140 150
IGDAAIVRVL TEAYGRKADQ IKAQMKTLGD LGLVAKASRT SQRTMFKSQP
160 170 180 190 200
LTCAKVLDTF REIAKDSGNQ SQDRKRGRMK ALLVAATECE PLYLVRLLQS
210 220 230 240 250
KLRIGLAEKT VLAALAHAAV LSEVPRVPAN QLTARLEEAE EIMKETYSVL
260 270 280 290 300
PIYEKIISAI LEHGIRKLPE VCNFTLGIPV GPMLAKPTTG VSEVLNKFQD
310 320 330 340 350
MEFSCEYKYD GERAQVHYLQ GGTIEIYSRN AEHNTGKFPD IVAAMPRCMK
360 370 380 390 400
TGTETYVLDC EVVAYDREKN KILPFQVLST RARKGVVLSD IKIQVCLFAF
410 420 430 440 450
DLLYLNGRPL LKEQLNVRRE LLYSSFQEIP GEFQFATAKN SNDLEEIQKF
460 470 480 490 500
LEDAINDSCE GLIVKTLSKD ATYEPAKRSN NWLKLKKDYM NTGGGDSLDL
510 520 530 540 550
VPIGAFYGRG KRVGVYGAFL LACYDEDREE FQSICKIGTG FTEAVLEERS
560 570 580 590 600
VTLKNHVIPQ PRSYYRYGET IGVDVWFEDV EVWEVKAADL SISPVHRAAV
610 620 630 640 650
GLVDPNKGIS LRFPRLMRLR EDKTPVEATS AQQVAEMYRA QKINHGHGGD

ADDDDD
Length:656
Mass (Da):72,907
Last modified:February 5, 2008 - v1
Checksum:iC5B853492DD5520E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS545112 Genomic DNA Translation: EDQ57593.1
RefSeqiXP_001777550.1, XM_001777498.1
UniGeneiPpa.12544

Genome annotation databases

EnsemblPlantsiPP1S223_54V6.1; PP1S223_54V6.1; PP1S223_54V6
GrameneiPP1S223_54V6.1; PP1S223_54V6.1; PP1S223_54V6
KEGGippp:PHYPADRAFT_221958

Similar proteinsi

Entry informationi

Entry nameiA9TG22_PHYPA
AccessioniPrimary (citable) accession number: A9TG22
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health