ID   A9T790_PHYPA            Unreviewed;       959 AA.
AC   A9T790;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   RecName: Full=phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00012305};
DE            EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305};
GN   ORFNames=PHYPA_008888 {ECO:0000313|EMBL:PNR52514.1};
OS   Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC   Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX   NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR52514.1};
RN   [1] {ECO:0000313|EMBL:PNR52514.1, ECO:0000313|Proteomes:UP000006727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c6_12940V3.1,
RC   ECO:0000313|Proteomes:UP000006727};
RX   PubMed=18079367; DOI=10.1126/science.1150646;
RA   Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA   Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA   Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA   Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA   Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA   Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA   Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA   Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA   Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA   Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA   Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA   Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA   Boore J.L.;
RT   "The Physcomitrella genome reveals evolutionary insights into the conquest
RT   of land by plants.";
RL   Science 319:64-69(2008).
RN   [2] {ECO:0000313|EMBL:PNR52514.1, ECO:0000313|Proteomes:UP000006727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c6_12940V3.1,
RC   ECO:0000313|Proteomes:UP000006727};
RX   PubMed=29237241; DOI=10.1111/tpj.13801;
RA   Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA   Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA   Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA   Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA   Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA   Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA   Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA   Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA   Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA   Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA   Schmutz J., Rensing S.A.;
RT   "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT   structure and evolution.";
RL   Plant J. 93:515-533(2018).
RN   [3] {ECO:0000313|EnsemblPlants:Pp3c6_12940V3.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (DEC-2020) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008346}.
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DR   EMBL; ABEU02000006; PNR52514.1; -; Genomic_DNA.
DR   RefSeq; XP_001774499.1; XM_001774447.1.
DR   AlphaFoldDB; A9T790; -.
DR   SMR; A9T790; -.
DR   STRING; 3218.A9T790; -.
DR   PaxDb; 3218-PP1S177_55V6-1; -.
DR   EnsemblPlants; Pp3c6_12940V3.1; Pp3c6_12940V3.1; Pp3c6_12940.
DR   EnsemblPlants; Pp3c6_12940V3.3; Pp3c6_12940V3.3; Pp3c6_12940.
DR   Gramene; Pp3c6_12940V3.1; Pp3c6_12940V3.1; Pp3c6_12940.
DR   Gramene; Pp3c6_12940V3.3; Pp3c6_12940V3.3; Pp3c6_12940.
DR   eggNOG; ENOG502QPVS; Eukaryota.
DR   HOGENOM; CLU_006557_2_0_1; -.
DR   InParanoid; A9T790; -.
DR   OMA; WRCNTEL; -.
DR   OrthoDB; 355614at2759; -.
DR   Proteomes; UP000006727; Chromosome 6.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IBA:GO_Central.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF33; PHOSPHOENOLPYRUVATE CARBOXYLASE 3; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006727}.
FT   REGION          906..937
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        906..932
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        171
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        599
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10112"
SQ   SEQUENCE   959 AA;  109086 MW;  7772355851F2D619 CRC64;
     MAFLKKIKSI DAPMRLLVPK KVSEDDMLVD YGSQLGNRFL DILESLHGKS MRETVMNCYE
     LAGAFANSHS REEEKLQQLS SLLNNLNPTD SIVVASSFSH MLNLGNLAEE IQIAYRRPTN
     KKGNIGDENS ALTESDLDQT FQRLKDELHK SPDEIFEALK KQTVDLVFTA HPTQSVRRSL
     LQKHSRIRDC LSQMYQKDVT AEEKQELDEA LQREIQAAFR TDEIRRSQPA PQDEMRAGMS
     YFHETIWNGL PKFLRRVDTA LKGIGVKERL PHDVPLIQFS SWMGGDRDGN PRVTPDVTRD
     VCLLARLMAA NLYYSQIEDL MFELSMWRCS DELKQRVAIL EAQTKKESKH YTEFWKHIPP
     NEPFRVLLGN MRDKLYNTRE RMRQLLANGK SDINLEDTFT EKSQILEPLE LCHRSLCETG
     DKPIADGSLL DFMRQVSCFG LSLVKLDIRQ ESDRHTDVLD TITNYLGIGS YRDWSEEQRQ
     DWLLSELRGR RPLFGPDMPT TEEVKDVLDT FKVIAELPED CFGAYIISMA TAPSDVLAVE
     LLQRESHIPT PLRVVPLFEK LADLESAPAT LSRLFSIDWY LSRINGKQEV MIGYSDSGKD
     AGRLSAAWQM FKAQEDLVKV AKQYEVRLTM FHGRGGTVGR GGGPTHLAIL SQPPDTINGS
     LRVTIQGEVI EQSFGEEHLC FRTLQRFTAA TLEHGMNPPI APEPEWRDLM DFMAVIATDE
     YRSIVFKNPR FVEYFRTATP ELEYGRMNIG SRPSKRKPSG GIESLRAIPW IFAWTQTRFH
     LPVWLGLGAA LKQALEAGPG NFDTLSRMYD LWPFFRVTID LVEMVFAKGD PRIAELYDNL
     LVPEELKPLG EELREKYNET KSHLLKIARH TDILQGNPTL KQRLRLREPV ITALNVQQAF
     TLKKMREQTG QGTQSESPKS TKPASDPVTL NPTTEFAPGL EDTMIITMKG IAAGIQNTG
//