ID   A9T5R9_PHYPA            Unreviewed;       958 AA.
AC   A9T5R9;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   RecName: Full=phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00012305};
DE            EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305};
GN   ORFNames=PHYPA_007669 {ECO:0000313|EMBL:PNR53993.1};
OS   Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC   Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX   NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR53993.1};
RN   [1] {ECO:0000313|EMBL:PNR53993.1, ECO:0000313|Proteomes:UP000006727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c5_14630V3.1,
RC   ECO:0000313|Proteomes:UP000006727};
RX   PubMed=18079367; DOI=10.1126/science.1150646;
RA   Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA   Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA   Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA   Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA   Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA   Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA   Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA   Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA   Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA   Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA   Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA   Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA   Boore J.L.;
RT   "The Physcomitrella genome reveals evolutionary insights into the conquest
RT   of land by plants.";
RL   Science 319:64-69(2008).
RN   [2] {ECO:0000313|EMBL:PNR53993.1, ECO:0000313|Proteomes:UP000006727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c5_14630V3.1,
RC   ECO:0000313|Proteomes:UP000006727};
RX   PubMed=29237241; DOI=10.1111/tpj.13801;
RA   Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA   Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA   Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA   Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA   Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA   Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA   Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA   Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA   Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA   Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA   Schmutz J., Rensing S.A.;
RT   "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT   structure and evolution.";
RL   Plant J. 93:515-533(2018).
RN   [3] {ECO:0000313|EnsemblPlants:Pp3c5_14630V3.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (DEC-2020) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008346}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ABEU02000005; PNR53993.1; -; Genomic_DNA.
DR   RefSeq; XP_001773964.1; XM_001773912.1.
DR   AlphaFoldDB; A9T5R9; -.
DR   SMR; A9T5R9; -.
DR   STRING; 3218.A9T5R9; -.
DR   PaxDb; 3218-PP1S169_156V6-1; -.
DR   EnsemblPlants; Pp3c5_14630V3.1; Pp3c5_14630V3.1; Pp3c5_14630.
DR   EnsemblPlants; Pp3c5_14630V3.2; Pp3c5_14630V3.2; Pp3c5_14630.
DR   Gramene; Pp3c5_14630V3.1; Pp3c5_14630V3.1; Pp3c5_14630.
DR   Gramene; Pp3c5_14630V3.2; Pp3c5_14630V3.2; Pp3c5_14630.
DR   eggNOG; ENOG502QPVS; Eukaryota.
DR   HOGENOM; CLU_006557_2_0_1; -.
DR   InParanoid; A9T5R9; -.
DR   OMA; WKSIPTT; -.
DR   OrthoDB; 355614at2759; -.
DR   Proteomes; UP000006727; Chromosome 5.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IBA:GO_Central.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF33; PHOSPHOENOLPYRUVATE CARBOXYLASE 3; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006727}.
FT   ACT_SITE        170
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        598
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10112"
SQ   SEQUENCE   958 AA;  109293 MW;  B37F556E04BD3190 CRC64;
     MAFLQKIKSI DASMRLLVPK KVSEDDMLVD YGAKLVDRSL AILENLHGKE MKDTVLECYE
     LAGAFCADSR NEEKLQQLSS LLNNLDAGDS IVVASSFSHM LNLENLAEEV QIAHRRPANK
     KGNIGDENSA LTESDLDQTF QRLVKKLKKS PEEIFEALKN QTVDLVFTAH PTQSVRRSLL
     QKHSRIRNCL SQMYQKDITA EEKQELDEAL QREIQAAFRT DEIRRSQPTP QDEMRAGMSY
     FHETIWNGLP KFLRRVDTAL KAIGVNKRLP HNVPLIQFSS WMGGDRDGNP RVTPDMTRDV
     CLLARLMAAN LYYSQIEDLM FELSMWRCSD ELRQRVAVLE AQPKKESKHY IEFWKQIPPS
     EPFRVLLGDM RDKLYNTREW MRQLLANGKS DVNRDNTFTE KSQILEPLEL CYRSLCETGD
     KPIADGSLLD FMRRVSCFGL SLVRLDIRQE SDRHTDVMDT ITNYLGIGSY RDWSEEQRQD
     WLLSELRGKR PLFGPGMPTS EEVKDVLDTF RVVAELPADC FGAYVISMAT APSDVLAVEL
     LQRECRIPTP LRVVPLFEKL ADLESAPASL SRLFSIDWYL NRINGKQEVM IGYSDSGKDA
     GRLSAAWQMF KAQENLLKVA KHYGVRLTMF HGRGGTVGRG GGPTHLAILS QPPDTINGSL
     RVTIQGEVIE QSFGEEHLCF RTLQRFTAAT LEHGMHPPIA PKPEWRDLMD SMAVVATDEY
     RSVVFKNPRF VEYFRMATPE LEYGRMNIGS RPSRRKPSGG IESLRAIPWI FAWTQTRFHL
     PVWLGLGAAL KRALEDNPSN FNTLYRMYDQ WPFFRVTIDL MEMVFAKGDP RIAQLYDDLL
     VADELKSLGI ELRQKYNETK EHLLKVARHT EILQGNPTLK QRLRLREPYI TALNVQQAFT
     LKKMREQHSQ LTQPDSPKPT KPAAELVTLN PTTEFAPGLE DTMILTMKGI AAGIQNTG
//