ID   A9RR67_PHYPA            Unreviewed;       489 AA.
AC   A9RR67;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   RecName: Full=Alliinase C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PHYPA_008116 {ECO:0000313|EMBL:PNR54439.1};
OS   Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC   Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX   NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR54439.1};
RN   [1] {ECO:0000313|EMBL:PNR54439.1, ECO:0000313|Proteomes:UP000006727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c5_24670V3.1,
RC   ECO:0000313|Proteomes:UP000006727};
RX   PubMed=18079367; DOI=10.1126/science.1150646;
RA   Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA   Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA   Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA   Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA   Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA   Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA   Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA   Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA   Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA   Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA   Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA   Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA   Boore J.L.;
RT   "The Physcomitrella genome reveals evolutionary insights into the conquest
RT   of land by plants.";
RL   Science 319:64-69(2008).
RN   [2] {ECO:0000313|EMBL:PNR54439.1, ECO:0000313|Proteomes:UP000006727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c5_24670V3.1,
RC   ECO:0000313|Proteomes:UP000006727};
RX   PubMed=29237241; DOI=10.1111/tpj.13801;
RA   Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA   Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA   Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA   Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA   Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA   Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA   Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA   Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA   Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA   Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA   Schmutz J., Rensing S.A.;
RT   "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT   structure and evolution.";
RL   Plant J. 93:515-533(2018).
RN   [3] {ECO:0000313|EnsemblPlants:Pp3c5_24670V3.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (DEC-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the alliinase family.
CC       {ECO:0000256|ARBA:ARBA00006312}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ABEU02000005; PNR54439.1; -; Genomic_DNA.
DR   RefSeq; XP_001756693.1; XM_001756641.1.
DR   AlphaFoldDB; A9RR67; -.
DR   STRING; 3218.A9RR67; -.
DR   PaxDb; 3218-PP1S23_275V6-1; -.
DR   EnsemblPlants; Pp3c5_24670V3.1; Pp3c5_24670V3.1; Pp3c5_24670.
DR   EnsemblPlants; Pp3c5_24670V3.2; Pp3c5_24670V3.2; Pp3c5_24670.
DR   EnsemblPlants; Pp3c5_24670V3.3; Pp3c5_24670V3.3; Pp3c5_24670.
DR   Gramene; Pp3c5_24670V3.1; Pp3c5_24670V3.1; Pp3c5_24670.
DR   Gramene; Pp3c5_24670V3.2; Pp3c5_24670V3.2; Pp3c5_24670.
DR   Gramene; Pp3c5_24670V3.3; Pp3c5_24670V3.3; Pp3c5_24670.
DR   eggNOG; ENOG502QQJV; Eukaryota.
DR   HOGENOM; CLU_036760_2_0_1; -.
DR   InParanoid; A9RR67; -.
DR   OMA; VMSSRWR; -.
DR   OrthoDB; 1275724at2759; -.
DR   Proteomes; UP000006727; Chromosome 5.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016846; F:carbon-sulfur lyase activity; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IBA:GO_Central.
DR   GO; GO:0006520; P:amino acid metabolic process; IBA:GO_Central.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 2.10.25.30; EGF-like, alliinase; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR006948; Alliinase_C.
DR   InterPro; IPR037029; Alliinase_N_sf.
DR   InterPro; IPR006947; EGF_alliinase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR43795:SF110; ALLIINASE_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43795; BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED; 1.
DR   Pfam; PF04864; Alliinase_C; 1.
DR   Pfam; PF04863; EGF_alliinase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006727};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          72..125
FT                   /note="Alliinase EGF-like"
FT                   /evidence="ECO:0000259|Pfam:PF04863"
FT   DOMAIN          128..485
FT                   /note="Alliinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04864"
SQ   SEQUENCE   489 AA;  53966 MW;  D4068418801CE825 CRC64;
     MEADDTSARL LPLASWQSTH KNSTEAKFSL RNVVLYVSLL VNLPALVIVF HPIQGFLWTP
     PRSEQPAAPQ WAEAVQAAER AASKWCSGNG NVFVDTVGID ADGSPSCECN DCFAGPDCSL
     PLPDCVADAI SGDPLLFEAY WRKNSDLGAV VIPAWYRMGY QTRDVTSMPY TEALVASIRE
     LHAMVGNAVT EGRYIAFGTG STQLINAVIH SLALQDPGRV TPVVSKAPYY NAYYTQTEYF
     KSPFYSFSGE PDRKVGQQGP AQIEVIASPN NPTTQIQEVP QNVSGHVVYD HAYYWPHLTP
     ITKAVDYDIM LFTLSKLTGH AGSRIGWVIL KDFDLYTKVL RYADVSTIGL GHEAQLRASQ
     LIRTIIDGYS EGNSGREGIF HFAHDVLQSR WAKLQAIFQN VSRFSLQELK PGYCSFFKRV
     SDPSPGYAWI RCNREEDADC SAVLLSAGII GRAGPIFGTT PRYVRLSLLK RASHFDNLAD
     HLLKLVAQS
//