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Protein

Hexokinase

Gene

hxk8

Organism
Physcomitrella patens subsp. patens (Moss)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:hxk8Imported
ORF Names:PHYPADRAFT_235449Imported
OrganismiPhyscomitrella patens subsp. patens (Moss)Imported
Taxonomic identifieri3218 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaFunariidaeFunarialesFunariaceaePhyscomitrella
ProteomesiUP000006727: Partially assembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi3218.JGI112282.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 2 hexokinase type-2 domains.UniRule annotation

Phylogenomic databases

InParanoidiA9RE02.
KOiK00844.
OMAiPHLMSGN.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9RE02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQSKAMAGV YIACAAAACA AAAVVLTQRV KVRSQKYTAR KILVEFQEAC
60 70 80 90 100
ETPLPRLRQV VDAMAVEMHA GLVSEGGSKL KMLPTFIDHL PDGNEKGLYY
110 120 130 140 150
AVDLGGTNFR VLRTQLGGLE GRVIKQEYEE VAIPPELMLG TSEQLFDFIA
160 170 180 190 200
KELVSFVARE GEDFRLHEGQ SREIGFTFSF PCKQTAVNSG TLLQWTKGFK
210 220 230 240 250
VNDAIGQDVV AALQGSIERR GYKMRIAALV NDTVGTLAGG RYWNNDVMIA
260 270 280 290 300
VILGTGTNAC YVERAESISK WGGELPKSGQ MVINMEWGNF WSSHLPRTYV
310 320 330 340 350
DELLDNESLN PGEYGFEKMI SGMYLGDCVR RVLVRMAQQA GIFGPHVPHK
360 370 380 390 400
LLEAFTLQTP DMSKMHHDDS SDLKMVAEVL KTVYGIHNTT LGIRKIVLAV
410 420 430 440 450
CDIVCQRGAR LAAAGIVGIL KKIGRDGSTA NGFIRRNDVN GIHDELTVNS
460 470 480 490 500
IGGSGKTVVA MDGGLYEHYS KFRNYMQQAV RELLGDAAKN VFIELSKDGS
510
GIGAAILAAS HAEYVPT
Length:517
Mass (Da):56,379
Last modified:February 5, 2008 - v1
Checksum:iC46DB4820D5C8A9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS544892 Genomic DNA. Translation: EDQ82962.1.
RefSeqiXP_001752229.1. XM_001752177.1.

Genome annotation databases

GeneIDi5915312.
KEGGippp:PHYPADRAFT_235449.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS544892 Genomic DNA. Translation: EDQ82962.1.
RefSeqiXP_001752229.1. XM_001752177.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3218.JGI112282.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5915312.
KEGGippp:PHYPADRAFT_235449.

Phylogenomic databases

InParanoidiA9RE02.
KOiK00844.
OMAiPHLMSGN.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants."
    Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H., Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T., Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A., Suzuki Y.
    , Hashimoto S.-I., Yamaguchi K., Sugano A., Kohara Y., Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E., Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M., Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J., Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B., Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A., Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y., Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M., Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S., Boore J.L.
    Science 319:64-69(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Gransden 2004Imported.

Entry informationi

Entry nameiA9RE02_PHYPA
AccessioniPrimary (citable) accession number: A9RE02
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: March 4, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.