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A9RAG9

- COX3_DEBHA

UniProt

A9RAG9 - COX3_DEBHA

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Protein

Cytochrome c oxidase subunit 3

Gene

COX3

Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Cytochrome oxidase subunit 3
Gene namesi
Name:COX3
Encoded oniMitochondrion
OrganismiDebaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Taxonomic identifieri284592 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeDebaryomyces
ProteomesiUP000000599: Mitochondrion

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Cytochrome c oxidase subunit 3PRO_0000355033Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi4959.A9RAG9.

Structurei

3D structure databases

ProteinModelPortaliA9RAG9.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4121HelicalSequence AnalysisAdd
BLAST
Transmembranei49 – 6921HelicalSequence AnalysisAdd
BLAST
Transmembranei90 – 11021HelicalSequence AnalysisAdd
BLAST
Transmembranei132 – 15221HelicalSequence AnalysisAdd
BLAST
Transmembranei167 – 18721HelicalSequence AnalysisAdd
BLAST
Transmembranei205 – 22521HelicalSequence AnalysisAdd
BLAST
Transmembranei247 – 26721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1845.
InParanoidiA9RAG9.
KOiK02262.
OrthoDBiEOG7V76HP.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9RAG9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTNNTRGYIQ LHPFHLVGPS PWPMFTSFSL MNLALSLGLT AHGYMNNNMF
60 70 80 90 100
MLLSTMTVLY SMTLWFKDIM AESTYLGDHT VAVKRGLMQG FLMFVVSEML
110 120 130 140 150
MFSSLFWAFL HSALNPTVEM GMSWPPAGME AISAAELPLL NTMILLASGV
160 170 180 190 200
TMTYAHHALM NGNRQNTLYG FAYSTLLMVL FVMFQGLEYT YAGFTITDGV
210 220 230 240 250
YGSTFFALTG LHGLHMMMLI MMLAMCTMRV YNYDFTNTSH VGAETTILYL
260
HVLDVMWLFM YMIVYWWGA
Length:269
Mass (Da):30,521
Last modified:February 5, 2008 - v1
Checksum:i64AD20631D0375BA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ508940 Genomic DNA. Translation: ABF58070.1.
RefSeqiYP_001621421.1. NC_010166.1.

Genome annotation databases

GeneIDi5845855.
KEGGidha:cox3.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ508940 Genomic DNA. Translation: ABF58070.1 .
RefSeqi YP_001621421.1. NC_010166.1.

3D structure databases

ProteinModelPortali A9RAG9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 4959.A9RAG9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5845855.
KEGGi dha:cox3.

Phylogenomic databases

eggNOGi COG1845.
InParanoidi A9RAG9.
KOi K02262.
OrthoDBi EOG7V76HP.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968.

Entry informationi

Entry nameiCOX3_DEBHA
AccessioniPrimary (citable) accession number: A9RAG9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: February 5, 2008
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3