A9R2M4 (DCD_YERPG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	YpAngola_A3194

Organism

Yersinia pestis bv. Antiqua (strain Angola) [Complete proteome] [HAMAP]

Taxonomic identifier

349746 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia › Yersinia pestis

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000096465

Sequences

	Sequence		Length	Mass (Da)
	A9R2M4 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: AF09C4C83A623BCE	FASTA	193	21,140
	10 20 30 40 50 60 MRLCDRDIEA WLDSGKLGIE PRPPVERING ATVDVRLGNQ FRVFRGHTAA FIDLSGPKDE 70 80 90 100 110 120 VSAALERVMS DEINLPEGEA FFLHPGELAL AVTLESVTIP DDLVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WQGRIVLEFY NSGKLPLALR PGMLIGALSF EPLSGPAARP YNSRQDAKYR 190 GQQGAVASRI DKD

References

[1]

"Genome sequence of the deep-rooted Yersinia pestis strain Angola reveals new insights into the evolution and pangenome of the plague bacterium." Eppinger M., Worsham P.L., Nikolich M.P., Riley D.R., Sebastian Y., Mou S., Achtman M., Lindler L.E., Ravel J. J. Bacteriol. 192:1685-1699(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Angola.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000901 Genomic DNA. Translation: ABX86816.1.
RefSeq	YP_001607550.1. NC_010159.1.
3D structure databases
ProteinModelPortal	A9R2M4.
SMR	A9R2M4. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	349746.YpAngola_A3194.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABX86816; ABX86816; YpAngola_A3194.
GeneID	5801669.
KEGG	ypg:YpAngola_A3194.
PATRIC	18575968. VBIYerPes97331_3746.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_YERPG

Accession

Primary (citable) accession number: A9R2M4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program