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A9R0L2 (A9R0L2_YERPG) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL ABX86689.1
Ordered Locus Names:YpAngola_A2848 EMBL ABX86689.1
OrganismYersinia pestis bv. Antiqua (strain Angola) [Complete proteome] [HAMAP] EMBL ABX86689.1
Taxonomic identifier349746 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
A9R0L2 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: F908FB962F0F4932

FASTA41745,868
        10         20         30         40         50         60 
MESKVVVPAE GKKITVDAQG KLVVPHNPII PFIEGDGIGV DVTPAMINVV DAAVKKAYNG 

        70         80         90        100        110        120 
ERKISWMEIY TGEKSTHVYG KDVWLPEETL DLIRDYRVAI KGPLTTPVGG GIRSLNVALR 

       130        140        150        160        170        180 
QQLDLYVCLR PVRYYEGTPS PVKHPELTNM VIFRENAEDI YAGIEWKAGS PEAEKVIKFL 

       190        200        210        220        230        240 
REEMGVKKIR FPEQCGIGVK PCSEEGTKRL VRAAIEYAIT NDRESVTLVH KGNIMKFTEG 

       250        260        270        280        290        300 
AFKDWGYQLA REEFGGELID GGPWVKIKNP NNGKEIIVKD VIADAFLQQI LLRPAEYDVI 

       310        320        330        340        350        360 
ACMNLNGDYI SDALAAQVGG IGIAPGANIG DDCALFEATH GTAPKYAGQD KVNPGSIILS 

       370        380        390        400        410 
AEMMLRHMGW FEAADLIIKG TEGAIQAKTV TYDFERLMEG AKLLKCSEFG DAIIKHM 

« Hide

References

[1]"Genome sequence of the deep-rooted Yersinia pestis strain Angola reveals new insights into the evolution and pangenome of the plague bacterium."
Eppinger M., Worsham P.L., Nikolich M.P., Riley D.R., Sebastian Y., Mou S., Achtman M., Lindler L.E., Ravel J.
J. Bacteriol. 192:1685-1699(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Angola EMBL ABX86689.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000901 Genomic DNA. Translation: ABX86689.1.
RefSeqYP_001607230.1. NC_010159.1.

3D structure databases

ProteinModelPortalA9R0L2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349746.YpAngola_A2848.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABX86689; ABX86689; YpAngola_A2848.
GeneID5801320.
KEGGypg:YpAngola_A2848.
PATRIC18575207. VBIYerPes97331_3366.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
OrthoDBEOG6SNDTP.
ProtClustDBPRK07006.

Enzyme and pathway databases

BioCycYPES349746:GHPB-2854-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9R0L2_YERPG
AccessionPrimary (citable) accession number: A9R0L2
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 13, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)