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A9QXB7 (A9QXB7_BOVIN) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Interferon gamma PIRNR PIRNR001936

Short name=IFN-gamma PIRNR PIRNR001936
OrganismBos taurus (Bovine) EMBL ABX75548.1
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length166 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons By similarity. PIRNR PIRNR001936

Subunit structure

Homodimer By similarity. PIRNR PIRNR001936

Subcellular location

Secreted By similarity PIRNR PIRNR001936.

Sequence similarities

Belongs to the type II (or gamma) interferon family. PIRNR PIRNR001936

Ontologies

Sequences

Sequence LengthMass (Da)Tools
A9QXB7 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 308268B950BB3B1F

FASTA16619,363
        10         20         30         40         50         60 
MKYTSYFLAL LLCGLLGFSG SYGQGQFFRE IENLKEYFNA SSPDVAKGGP LFSEILKNWK 

        70         80         90        100        110        120 
DESDKKIIQS QIVSFYFKLF ENLKDNQVIQ RSMDIIKQDM FQKFLNGSSE KLEDFKKLIQ 

       130        140        150        160 
IPVDDLQIQR KAINELIKVM NDLSPKSNLR KRKRSQNLFR GRRAST 

« Hide

References

[1]"Cloning and sequence analysis of the interferon gamma gene of Chinese cow."
Qiao J., Chen C., Meng Q.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Expression of bovine interferon gamma in eukaryotic cells."
Nikbakht G.H., Jalali A.H., Emam S.M.
Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EU277737 mRNA. Translation: ABX75548.1.
FJ263670 mRNA. Translation: ACI49698.1.
RefSeqNP_776511.1. NM_174086.1.
UniGeneBt.188.

3D structure databases

ProteinModelPortalA9QXB7.
SMRA9QXB7. Positions 24-144.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEA9QXB7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID281237.
KEGGbta:281237.

Organism-specific databases

CTD3458.

Phylogenomic databases

HOVERGENHBG056912.
InParanoidA9QXB7.
KOK04687.

Family and domain databases

Gene3D1.20.1250.10. 1 hit.
InterProIPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR002069. Interferon_gamma.
[Graphical view]
PANTHERPTHR11419. PTHR11419. 1 hit.
PfamPF00714. IFN-gamma. 1 hit.
[Graphical view]
PIRSFPIRSF001936. IFN-gamma. 1 hit.
ProDomPD002435. Interferon_gamma. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF47266. SSF47266. 1 hit.
ProtoNetSearch...

Other

NextBio20805283.

Entry information

Entry nameA9QXB7_BOVIN
AccessionPrimary (citable) accession number: A9QXB7
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: January 22, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)