A9QVL3 (A9QVL3_MANSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Sodium/hydrogen exchanger RuleBase RU003722
Organism	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) EMBL ABX71221.1
Taxonomic identifier	7130 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Amphiesmenoptera › Lepidoptera › Glossata › Neolepidoptera › Heteroneura › Ditrysia › Obtectomera › Bombycoidea › Sphingidae › Sphinginae › Sphingini › Manduca

Protein attributes

Sequence length	630 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. [View classification] RuleBase RU003722

Ontologies

Keywords
Biological process	Antiport RuleBase RU003722 Ion transport Sodium transport SAAS SAAS006153 RuleBase RU003722 Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS018422
Ligand	Sodium
Gene Ontology (GO)
Biological_process	regulation of pH Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	sodium:hydrogen antiporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9QVL3 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 2AD4A3F3DEF760BB	FASTA	630	69,849
	10 20 30 40 50 60 MKTLYKLSRP KRASEGNVTS SSEASNIETV ESTSPNPPPE NVNPVYDIGS SNSSLFSITQ 70 80 90 100 110 120 VNISSSATPN VSVNPSDAAP LPEKSSAEDE HNSSMAIFFV LCILALGILL IHLMLQTGFS 130 140 150 160 170 180 YLPESVVIVF LGALIGMIIN LMSIKNIANW RKEEAFSPTA FFLVLLPPII FESGYNLHKG 190 200 210 220 230 240 NFFQNIGSIL LFAIVGTAIS AFVIGAGIYL LGLAQVVYKL SFVESFAFGS LISAVDPVAT 250 260 270 280 290 300 VAIFHALDVD PVLNMLVFGE SILNDAVAIV LTTAVLDSND PHMSTGEAIL SAINRFWLMF 310 320 330 340 350 360 FASAGIGVLF ALVSALLLKH VDLRKNPSLE FGMMLVFTYA PYVLAEGIHL SGIMAILFCG 370 380 390 400 410 420 IVMSHYTHFN LSAVTQVTMQ QTMRTLAFIA ETCVFAYLGL AIFSFRHRVE PALVVWSIVM 430 440 450 460 470 480 CLLGRAANIF PLALLCNKFR EHKITKKMMF IMWFSGLRGA ISYALSLHLG FSDETRHVII 490 500 510 520 530 540 TTTLIIVLFT TLFFGGSTMP LLKFLRANKK TKRSRSLRKQ KEVSLSKTKE WGQAIDSEHL 550 560 570 580 590 600 SEITEEELEV NYSHATRLRG FVRLDMKYLT PFFTRRFTHQ ELKDCKSQMT DLTNQWYQAI 610 620 630 RISNDRETDE EESLQQSSLS NSHSSLQRGV

References

[1]

"Amiloride and its effect on ammonia uptake and potassium-dependent Isc in the midgut of the tobacco hornworm Manduca sexta L: Transport studies and mRNA expression analysis of NHE6 and NHE8." Weihrauch D., Blaesse A.-K., Broehan G., Meyer H. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Median midgut EMBL ABX71221.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU272023 mRNA. Translation: ABX71221.1.
3D structure databases
ProteinModelPortal	A9QVL3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR006153. Cation/H_exchanger. IPR018422. Cation/H_exchanger_CPA1. IPR018409. Na/H_exchanger_8_eu. IPR004709. NaH_exchanger. [Graphical view]
PANTHER	PTHR10110. PTHR10110. 1 hit. PTHR10110:SF9. PTHR10110:SF9. 1 hit.
Pfam	PF00999. Na_H_Exchanger. 1 hit. [Graphical view]
PRINTS	PR01084. NAHEXCHNGR.
TIGRFAMs	TIGR00840. b_cpa1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9QVL3_MANSE

Accession

Primary (citable) accession number: A9QVL3

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	October 3, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)