##gff-version 3 A9Q1D5 UniProtKB Transit peptide 1 50 . . . Note=Mitochondrion;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Chain 51 601 . . . ID=PRO_0000384394;Note=DNA topoisomerase I%2C mitochondrial A9Q1D5 UniProtKB Domain 268 601 . . . Note=Topo IB-type catalytic;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01382 A9Q1D5 UniProtKB Region 22 48 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite A9Q1D5 UniProtKB Region 261 262 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Region 324 329 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Region 421 423 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Active site 559 559 . . . Note=O-(3'-phospho-DNA)-tyrosine intermediate;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01382,ECO:0000255|PROSITE-ProRule:PRU10130 A9Q1D5 UniProtKB Site 152 152 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Site 200 200 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Site 248 248 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Site 279 279 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Site 337 337 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Site 368 368 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Site 410 410 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Site 468 468 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250 A9Q1D5 UniProtKB Site 486 486 . . . Note=Interaction with DNA;Ontology_term=ECO:0000250;evidence=ECO:0000250