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A9NHX0

- G6PI_ACHLI

UniProt

A9NHX0 - G6PI_ACHLI

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Acholeplasma laidlawii (strain PG-8A)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei279 – 2791Proton donorUniRule annotation
    Active sitei300 – 3001UniRule annotation
    Active sitei413 – 4131UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciALAI441768:GI40-1358-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:ACL_1358
    OrganismiAcholeplasma laidlawii (strain PG-8A)
    Taxonomic identifieri441768 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeAcholeplasma
    ProteomesiUP000008558: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 423423Glucose-6-phosphate isomerasePRO_1000081229Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi441768.ACL_1358.

    Structurei

    3D structure databases

    ProteinModelPortaliA9NHX0.
    SMRiA9NHX0. Positions 2-423.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiQVIFIGN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A9NHX0-1 [UniParc]FASTAAdd to Basket

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    MIKLDIKDAK KFLKTNVFSL QDQVNELHDV IQNKSGLGND FLGWLDLPLT    50
    YDKEELDRIY KLKEQHKNVD AIVVIGIGGS YLGAKAGYEF LKTPFKKQKP 100
    ELIFAGHHLS ANYLKHLLKY LNKKNYVINV ISKSGTTTEP AVAFRLLKAH 150
    IENKYGVKEA RKRIFATTDK ARGSLYQLAI NEGYERFVIE DNVGGRFSVL 200
    SAVGLLPFVF VGIDVEKMIK GAQDAYHDAQ DPSLKKNKAY LYAVTRFLLN 250
    QSGKDVEYLI NYEPRLAFFA EWWKQLFGES EGKGGKGLLV HSASFTTDLH 300
    SLGQQIQDGN RIIFETVLNV KKTDKLSIPF VEEDLDKLNY IAGKEISYVN 350
    EQAFLGTKEA HIDGGVPNIV ITIDKMDAYH FGYLVYFFEI ACAMSAYLLE 400
    VNPFDQPGVE AYKKNMFRLL GKK 423
    Length:423
    Mass (Da):47,924
    Last modified:February 5, 2008 - v1
    Checksum:i9BF7BB9E277CC5CC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000896 Genomic DNA. Translation: ABX81950.1.
    RefSeqiYP_001621326.1. NC_010163.1.

    Genome annotation databases

    EnsemblBacteriaiABX81950; ABX81950; ACL_1358.
    GeneIDi5804060.
    KEGGiacl:ACL_1358.
    PATRICi20639406. VBIAchLai134690_1303.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000896 Genomic DNA. Translation: ABX81950.1 .
    RefSeqi YP_001621326.1. NC_010163.1.

    3D structure databases

    ProteinModelPortali A9NHX0.
    SMRi A9NHX0. Positions 2-423.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 441768.ACL_1358.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABX81950 ; ABX81950 ; ACL_1358 .
    GeneIDi 5804060.
    KEGGi acl:ACL_1358.
    PATRICi 20639406. VBIAchLai134690_1303.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi QVIFIGN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci ALAI441768:GI40-1358-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PG-8A.

    Entry informationi

    Entry nameiG6PI_ACHLI
    AccessioniPrimary (citable) accession number: A9NHX0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3